Results 111 to 120 of about 6,778,249 (313)

Are General Relativity and Teleparallel Gravity Theoretically Equivalent?

open access: yesPhilosophy of Physics
Teleparallel gravity shares many qualitative features with general relativity, but differs from it in the following way: whereas in general relativity, gravitation is a manifestation of spacetime curvature, in teleparallel gravity, spacetime is (always)
James Owen Weatherall, Helen Meskhidze
doaj   +1 more source

Space and time in special relativity [PDF]

open access: yesRevista Brasileira de Ensino de Física
In this review of the kinematic part of Einstein’s Theory of Special Relativity, the physical meaning of the Lorentz Transformations is elucidated from basic physical facts that, although implicit in the formulation of the theory, are usually overlooked ...
Valdir Bindilatti
doaj   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Quantum Gravity as a Broken Symmetry Phase of a BF Theory

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2006
We explain how General Relativity with a cosmological constant arises as a broken symmetry phase of a BF theory. In particular we show how to treat de Sitter and anti-de Sitter cases simultaneously.
Aleksandar Miković
doaj  

On curved spacetime [PDF]

open access: yes
Albert Einstein’s theory of General Relativity was once the leading theory in theoretical physics. Unfortunately the theory describes macroscopic reality without a clear link with the the microcosm in respect to the properties of spacetime.
Grimm, Sydney Ernest
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Einstein, Gödel, Heidegger. Some observations about the concept of time

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2013
In this article we focus on some of the paths which help us to understand the philosophical question of time. The interpretative frame is composed of Einstein’s theory of relativity, against which we have the observations of Gödel and Heidegger on this ...
Diego Malquori
doaj  

Theory-Relative Skepticism

open access: yesDialectica, 1987
Summary This essay explores analogies between classical notions of pyrrhonist skepticism and reflexive phenomena of twentieth-century metamathematics. In a (first order) theoretical framework T, for example, one may interpret 1 T's appearances () as its axioms; 2 evident and inevident assertions () in the language L(T) of T as sentences ...
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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