Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
NMR RELAXATION METHODS TO DETECT PROTEIN DYNAMICS: EVALUATION OF ACCURACY, IMPROVEMENT OF THE METHODOLOGY, AND ITS APPLICATION [PDF]
, 2013 Proteins are dynamic molecules whose ability to undergo conformational changes and fluctuations can impact their biological function, such as enzyme catalysis and substrate recognition. Mutations or perturbations that do not significantly change protein
Myint, Wazo
core
An Investigation into the Effect of Employing Relaxation and Attention Deviation Methods on Alleviating Pain in Children Hospitalized in State Hospitals [PDF]
Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī, 2012 Pain is the most common type of stress encountered by humans, especially children. Medications and non-pharmaceutical techniques are used to control pain.
hosein ghamarigivi +1 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Effect of Benson's Versus Jacobson's Relaxation Methods on Primigravida Sleep Quality [PDF]
International Egyptian Journal of Nursing Sciences and ResearchBackground: During the third trimester, 75% of pregnant women have sleep issues, which has adetrimental effect on the mother. Benson and Jacobson's relaxation methods can significantly improve thequality of sleep during this crucial period.
Hanaa Shahin, Heba Osman, Amal Khalil
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Methods for Designing High-Precision Relaxation Oscillator
MicromachinesA novel low-power delay time cancellation (LPDTC) technique and a current ratio adjustment (CRA) method are proposed for designing high-precision relaxation oscillators.
Zhibo Huang +5 more
doaj +1 more source
Relaxation Methods To Reduce Pain And Injuries SEFT Post Sectio Caesaria
Jurnal Riset Kesehatan, 2015 Various ways are used to eliminate or reduce pain during childbirth with spontaneous or with Sectio Caesarian birth using non-pharmacological and pharmacological.
Sugih Wijayati +2 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
ranocha/Relaxation-LMM-notebooks
, 2020 General Relaxation Methods for Initial-Value Problems with Application to Multistep ...
David I. Ketcheson, Hendrik Ranocha
core +1 more source