Results 61 to 70 of about 390,758 (311)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Revisiting lagrange relaxation (LR) for processing large-scale mixed integer programming (MIP) problems [PDF]
Lagrangean Relaxation has been successfully applied to process many well known instances of NP-hard Mixed Integer Programming problems. In this paper we present a Lagrangean Relaxation based generic solver for processing Mixed Integer Programming ...
Siamitros, C, Mitra, G, Poojari, CA
core
Measuring and Modeling Viscoelastic Relaxation of the Lithosphere with Application to the Northern Volcanic Zone, Iceland [PDF]
Viscoelastic relaxation of the stress perturbation caused by an earthquake or diking event can produce measurable ground deformation over 100 km away from the source. We consider the role of viscoelastic relaxation in two different contexts.
DiCaprio, Christopher John
core +1 more source
PHYSICAL METHODS OF FAST REACTIONS INVESTIGATION [PDF]
This review presents the basic concepts of the methods used for investigation of fast reactions kinetics, such as: flow methods, with particular emphasis on the stopped-flow approach, NMR, ESR, electrochemical methods, with particular emphasis on the ...
Gheorghe Duca +2 more
doaj
Speaking skills are very important along with the times, so they must be trained early so that speaking skills do not become an obstacle in the future. This study uses qualitative methods with experimental types and comparative descriptive analysis.
Dyah Luthfia Kirana
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Stress relaxation models with polyconvex entropy in Lagrangean and Eulerian coordinates [PDF]
The embedding of the equations of polyconvex elastodynamics to an augmented symmetric hyperbolic system provides in conjunction with the relative entropy method a robust stability framework for approximate solutions \cite{LT06}.
Tzavaras, Athanasios E.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Background Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly being proposed as imaging biomarkers potentially capable of detecting biochemical changes in articular cartilage before structural changes are evident.
Hayden F. Atkinson +7 more
doaj +1 more source
High Order Relaxation Methods for Co-simulation of Finite Element and Circuit Solvers
Coupled problems result in very stiff problems whose char- acteristic parameters differ with several orders in magni- tude. For such complex problems, solving them monolithi- cally becomes prohibitive.
J. D. Nshimiyimana +4 more
doaj +1 more source

