Results 31 to 40 of about 128,348 (264)

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Reliability-Based and Cost-Oriented Product Optimization Integrating Fuzzy Reasoning Petri Nets, Interval Expert Evaluation and Cultural-Based DMOPSO Using Crowding Distance Sorting

open access: yesApplied Sciences, 2017
In reliability-based and cost-oriented product optimization, the target product reliability is apportioned to subsystems or components to achieve the maximum reliability and minimum cost.
Zhaoxi Hong   +4 more
doaj   +1 more source

Reliability-Based Optimal Design of Water Distribution Networks [PDF]

open access: yesJournal of Water Resources Planning and Management, 2001
A considerable amount of research has been carried out on the reliability analysis and optimal design of water distribution systems, and it has been reported that each of the above problems is very difficult to solve (Eiger et al. 1994; Wagner et al. 1988).
Tanyimboh, T.   +3 more
openaire   +3 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Reliability based design optimization of concrete mix proportions using generalized ridge regression model

open access: yesInternational Journal of Science and Engineering, 2015
This paper presents Reliability Based Design Optimization (RBDO) model to deal with uncertainties involved in concrete mix design process. The optimization problem is formulated in such a way that probabilistic concrete mix input parameters showing ...
Rachna Aggarwal   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Reliability based design optimization of a two-stage wind turbine gearbox

open access: yesMechanics & Industry
This paper describes a multi-objective reliability-based design optimization (MORBDO) of a two-stage wind turbine gearbox. The optimization process incorporates the gear's reliability of accounting for the uncertainty of its internal geometric parameters.
Karmi Bilel   +6 more
doaj   +1 more source

Interactive methodology for reliability-based structural design and optimization

open access: yesComputer Assisted Methods in Engineering and Science, 2023
Recent advances in reliability methods, optimization as well as design sensitivity analysis have resulted in development of computational systems supporting RBDO processes for medium/large structures. For RBDO the efficiency problems are critical and in
Rafał Stocki   +2 more
doaj  

Modified Single-Loop-Single-Vector Method for Efficient Reliability-Based Design Optimization

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
Single-Loop-Single-Vector (SLSV) method is to resolve the excessive computational cost problem in the reliability-based design optimization (RBDO) by decoupling the nested iteration loops.
Nozomu KOGISO   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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