Results 101 to 110 of about 3,372,734 (329)

A Fast Optimization Method for Reliability and Performance of Cloud Services Composition Application

Journal of Applied Mathematics, 2013
At present the cloud computing is one of the newest trends of distributed computation, which is propelling another important revolution of software industry. The cloud services composition is one of the key techniques in software development.
Zhao Wu, Naixue Xiong, Yannong Huang, Qiong Gu, Chunyang Hu, Zhongbo Wu, Bo Hang   +6 more
doaj   +1 more source

Reliability-based design optimization of shells with uncertain geometry using adaptive Kriging metamodels

, 2017
Optimal design under uncertainty has gained much attention in the past ten years due to the ever increasing need for manufacturers to build robust systems at the lowest cost.
Bourinet, J. -M., Dubourg, V., Sudret, B.   +2 more
core  

Classification-Based Method of Linear Multicriteria Optimization [PDF]

, 2003
The paper describes a classification-based learning-oriented interactive method for solving linear multicriteria optimization problems. The method allows the decision makers describe their preferences with greater flexibility, accuracy and reliability.
Genova, Krassimira, Narula, Subhash, Vassilev, Vassil, Vassileva, Mariyana   +3 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

ADVANCES IN RELIABILITY OPTIMIZATION OF MULTI-STATE SYSTEM

Jixie qiangdu, 2016
Multi-state system reliability is very important for complex systems which have a range of performance levels from perfect functioning to complete failure.
LI ChunYang, CHEN ShouHua, LI LingWei
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Discrete multicriteria reliability-based optimization of spatial trusses

Computer Assisted Methods in Engineering and Science, 2022
The paper presents problem of discrete multicriteria optimization of two-layer regular orthogonal spatial trusses. Three criteria of evaluation are taken into account, namely: minimum of weight, maximum of reliability and maximum of stiffness of the ...
Stefan Jendo, Witold M. Paczkowski, Ewa Silicka   +2 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Multidisciplinary Reliability Design Optimization Modeling Based on SysML

Applied Sciences
Model-Based Systems Engineering (MBSE) supports the system-level design of complex products effectively. Currently, system design and optimization for complex products are two distinct processes that must be executed using different software or platforms,
Qiang Zhang, Jihong Liu, Xu Chen
doaj   +1 more source