Results 91 to 100 of about 3,372,734 (329)
Reliability-based optimization of steel structures using genetic algorithms and nonlinear finite elements [PDF]
, 2015 Congreso celebrado en la Escuela de Arquitectura de la Universidad de Sevilla desde el 24 hasta el 26 de junio de 2015.Uncertainties are inherent in material properties, geometry parameters and loading in structural design problems. In a realistic design,
Celorrio Barragué, Luis
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Ultra-Reliable Low Latency Communication (URLLC) using Interface Diversity
, 2017 An important ingredient of the future 5G systems will be Ultra-Reliable Low-Latency Communication (URLLC). A way to offer URLLC without intervention in the baseband/PHY layer design is to use interface diversity and integrate multiple communication ...
Liu, Rongkuan +2 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Advances in Mechanical Engineering, 2018 Conventional decoupling approaches usually employ first-order reliability method to deal with probabilistic constraints in a reliability-based design optimization problem.
Zhiliang Huang +2 more
doaj +1 more source
Reliability-Based Structural Optimization of Wave Energy Converters
Energies, 2014 More and more wave energy converter (WEC) concepts are reaching prototypelevel. Once the prototype level is reached, the next step in order to further decrease thelevelized cost of energy (LCOE) is optimizing the overall system with a focus on ...
Simon Ambühl +2 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Researches of the decoupled method for reliability-based optimization [PDF]
, 2016 可靠性优化设计方法是工程结构设计中的一种非常具有优势的设计方法，其中，该方法的求解效率和求解精度是研究的重点。解耦策略是解决结构可靠性优化设计中包含复杂或隐式极限状态、多设计变量、小失效概率问题的一种高效可行的办法，它的关键在于建立失效概率的近似表达式，也就是求解失效概率函数。因此，研究高效求解失效概率函数近似的方法，以及提高优化效率和精度的解耦优化策略对于解决工程结构中的可靠性优化设计问题具有重要的作用。本文围绕上述问题展开研究工作，主要内容包括如下几个部分。 1.基于失效概率函数的概念 ...
朱海燕
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source