Results 71 to 80 of about 3,372,734 (329)

Reliability‐based layout optimization in offshore wind energy systems

Wind Energy, 2022
Existing methods for optimizing wind array layouts typically use power or cost objectives and rarely consider reliability‐based objectives. Component and system failure rates, however, are dependent on location‐specific wind conditions, are influenced by
Caitlyn E. Clark, Garrett Barter, Kelsey Shaler, Bryony DuPont   +3 more
doaj   +1 more source

Homotopy methods for constraint relaxation in unilevel reliability based design optimization [PDF]

, 2007
Reliability based design optimization is a methodology for finding optimized designs that are characterized with a low probability of failure. The main ob jective in reliability based design optimization is to minimize a merit function while satisfying
Agarwal, Harish, Gano, Shawn E., Perez, Victor M., Renaud, John E., Watson, Layne T.   +4 more
core  

Reliability‐Based Multidisciplinary Design Optimization under Correlated Uncertainties [PDF]

Mathematical Problems in Engineering, 2017
Complex mechanical system is usually composed of several subsystems, which are often coupled with each other. Reliability‐based multidisciplinary design optimization (RBMDO) is an efficient method to design such complex system under uncertainties. However, the present RBMDO methods ignored the correlations between uncertainties.
Huanwei Xu, Xin Wang, Wei Li, Mufeng Li, Suichuan Zhang, Cong Hu   +5 more
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Reliability optimization of systems with component improvement cost based on importance measure

Advances in Mechanical Engineering, 2018
The reliability optimization problem arises along with the increasing demands for products’ performance in practical engineering. Importance measures are capable of selecting critical components to gain the greatest improvement in system reliability with
Ning Wang, Jiang-bin Zhao, Zhong-yu Jiang, Shuai Zhang   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Reliability based design optimization of a two-stage wind turbine gearbox

Mechanics & Industry
This paper describes a multi-objective reliability-based design optimization (MORBDO) of a two-stage wind turbine gearbox. The optimization process incorporates the gear's reliability of accounting for the uncertainty of its internal geometric parameters.
Karmi Bilel, Saouab Abdelghani, Guerine Ahmed, Bouaziz Slim, EL Hami Abdelkhalak, Haddar Mohamed, Dammak Khalil   +6 more
doaj   +1 more source

Reliability-Based and Cost-Oriented Product Optimization Integrating Fuzzy Reasoning Petri Nets, Interval Expert Evaluation and Cultural-Based DMOPSO Using Crowding Distance Sorting

Applied Sciences, 2017
In reliability-based and cost-oriented product optimization, the target product reliability is apportioned to subsystems or components to achieve the maximum reliability and minimum cost.
Zhaoxi Hong, Yixiong Feng, Zhongkai Li, Guangdong Tian, Jianrong Tan   +4 more
doaj   +1 more source

Interactive Reliability-Based Optimal Design [PDF]

, 1995
Interactive design/optimization of large, complex structural systems is considered. The objective function is assumed to model the expected costs. The constraints are reliability-based and/or related to deterministic code requirements. Solution of this optimization problem is divided in four main tasks, namely finite element analyses, sensitivity ...
J. D. Sørensen, P. Thoft-Christensen, A. Siemaszko, J. M. B. Cardoso, J. L. T. Santos   +4 more
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source