Results 81 to 90 of about 24,217,389 (293)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Reliability-Based Structural Optimization of Wave Energy Converters
Energies, 2014 More and more wave energy converter (WEC) concepts are reaching prototypelevel. Once the prototype level is reached, the next step in order to further decrease thelevelized cost of energy (LCOE) is optimizing the overall system with a focus on ...
Simon Ambühl +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Algorithms for Reliability-Based Optimal Design [PDF]
, 1995 We present a new formulation for a class of structural optimization problems with reliability constraints, which makes it possible to use a new outer approximations algorithm for their solution. Our numerical results support the viability of our approach.
C. Kirjner-Neto, E. Polak, A. Kiureghian
openaire +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
, 2018 © 2017, Springer-Verlag GmbH Germany. In this paper, a new non-probabilistic reliability-based topology optimization (NRBTO) method is proposed to account for interval uncertainties considering parametric correlations.
Luo, Z, Wu, J, Ni, B, Jiang, C, Zheng, J
core +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Reliability assessment of cutting tools life based on advanced approximation methods [PDF]
, 2013 Cutting tools' reliability influences the whole manufacturing efficiency. However, in most cases the same cutting tool may be used for different operations with different processing parameters, making thus difficult to estimate the remaining life of the ...
Salonitis, Konstantinos +2 more
core +1 more source
Advances in Mechanical Engineering, 2018 Conventional decoupling approaches usually employ first-order reliability method to deal with probabilistic constraints in a reliability-based design optimization problem.
Zhiliang Huang +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source