Results 31 to 40 of about 1,215,775 (244)

Optimal Design of Accelerated Life Test Plan for Test Standard of a Manufacturer Making Multi-Series Products

open access: yesIEEE Access, 2019
To win fierce competition, a manufacturer would produce multi-series products to meet the diverse needs of customers. These products shall comply with the same test standard to estimate reliability before being launched into market.
Zixuan Pei, Yunxia Chen, Kunsong Lin
doaj   +1 more source

A Short-Term Hybrid TCN-GRU Prediction Model of Bike-Sharing Demand Based on Travel Characteristics Mining

open access: yesEntropy, 2022
This paper proposes an accurate short-term prediction model of bike-sharing demand with the hybrid TCN-GRU method. The emergence of shared bicycles has provided people with a low-carbon, green and healthy way of transportation.
Shenghan Zhou   +5 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Belief Reliability Distribution Based on Maximum Entropy Principle

open access: yesIEEE Access, 2018
Belief reliability is a new reliability metric based on the uncertainty theory, which aims to measure system performance incorporating the influences from design margin, aleatory uncertainty, and epistemic uncertainty.
Tianpei Zu   +3 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Reliability updating with equality information [PDF]

open access: yesProbabilistic Engineering Mechanics, 2011, 26(2): 254-258, 2012
In many instances, information on engineering systems can be obtained through measurements, monitoring or direct observations of system performances and can be used to update the system reliability estimate. In structural reliability analysis, such information is expressed either by inequalities (e.g.
arxiv   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Computation of Reliability Statistics for Success-Failure Experiments [PDF]

open access: yesarXiv, 2023
Reliability is probability of success in a success-failure experiment. Confidence in reliability estimate improves with increasing number of samples. Assurance sets confidence level same as reliability to create one number for easier communication.
arxiv  

Probabilistic Fatigue Crack Growth Analysis Under Stationary Random Loading With Spike Loads

open access: yesIEEE Access, 2018
The in-service loading condition of many engineering structures is generally composed of a stationary random loading caused by the mechanical vibration, and the spike loads due to occasional events, such as the sudden shock and accidental turbulence.
Shan Jiang, Wei Zhang, Zili Wang
doaj   +1 more source

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