Results 41 to 50 of about 1,392,566 (249)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

A Short-Term Hybrid TCN-GRU Prediction Model of Bike-Sharing Demand Based on Travel Characteristics Mining

open access: yesEntropy, 2022
This paper proposes an accurate short-term prediction model of bike-sharing demand with the hybrid TCN-GRU method. The emergence of shared bicycles has provided people with a low-carbon, green and healthy way of transportation.
Shenghan Zhou   +5 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

An Integral Formulation of Two-Parameter Fatigue Crack Growth Model

open access: yesAdvances in Materials Science and Engineering, 2018
A two-parameter fatigue crack growth algorithm in integral form is proposed, which can describe the continuous crack growth process over the time period.
Jianguo Wu   +3 more
doaj   +1 more source

Reliable broadcasting

open access: yesDiscrete Applied Mathematics, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
GARGANO, Luisa   +3 more
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Prognostic and Remaining Life Prediction of Electronic Device under Vibration Condition Based on CPSD of MPI

open access: yesShock and Vibration, 2016
Prognostic of electronic device under vibration condition can help to get information to assist in condition-based maintenance and reduce life-cycle cost.
Ying Chen, Ning Tang, Zenghui Yuan
doaj   +1 more source

Data reliability

open access: yesProceedings of the international conference on Reliable software -, 1975
This paper surveys the problems of achieving data reliability, and finds them more severe than those of program reliability. It then outlines some of the conceptual and methodological tools which are available for the solution of these problems, including the concept of type, direct product, union, sequence, recursion and mapping.
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Skill Vehicle Routing Problem With Time Windows Considering Dynamic Service Times and Time-Skill-Dependent Costs

open access: yesIEEE Access, 2019
Service processes in modern logistic systems tend to be highly specialized and intellectualized. However, some casual and unexpected behavior may occur, causing specific dynamic interactions among their many constituents.
Xiaoyuan Yan   +5 more
doaj   +1 more source

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