Results 51 to 60 of about 1,661,356 (249)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
IEEE Access, 2019 Space solar cell components always suffered from the complex and hostile space environment. The reliability of space solar cell components is important to ensure the mission success of space satellites.
Bo Sun +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Test-retest reliability of the human functional connectome over consecutive days: identifying highly reliable portions and assessing the impact of methodological choices [PDF]
, 2020 Leonardo Tozzi +4 more
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
IEEE Access, 2018 Uncertainty analyses have been considered critical analysis methods for identifying the risks in reliability evaluations. However, with multi-phase, multi-state, and repairable features, this method cannot effectively and precisely display the ...
Yi Ren +5 more
doaj +1 more source
The Use of a Fault Tree Analysis (FTA) in the Operator Reliability Assessment of the Critical Infrastructure on the Example of Water Supply System [PDF]
, 2022 Krzysztof Boryczko +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Temperature Compensation of FBG Sensor for Monitoring the Stress on Hole-Edge
IEEE Photonics Journal, 2018 To apply Fiber Bragg Grating (FBG) sensors in the hole structural health monitoring of aircraft, this study investigates a temperature compensation algorithm based on Fourier curve-fitting, combined with an analysis of FBG layout.
Feifei Ren +5 more
doaj +1 more source
Analysis of University Students’ Behavior Based on a Fusion K-Means Clustering Algorithm
Applied Sciences, 2020 With the development of big data technology, creating the ‘Digital Campus’ is a hot issue. For an increasing amount of data, traditional data mining algorithms are not suitable. The clustering algorithm is becoming more and more important in the field of
Wenbing Chang +6 more
doaj +1 more source