Results 71 to 80 of about 1,661,356 (249)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Investigating the reliability of estimating real-time air exchange rates in a building by using airborne particles, including PM1.0, PM2.5, and PM10: A case study in Suzhou, China

, 2023
Nuodi Fu, Moon Keun Kim, Long Huang, Jiying Liu, Bing Chen, Steve Sharples   +5 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Health assessment of a brushless direct current motor stator using a physics-informed long short-term memory network

International Journal of Electrical Power & Energy Systems
The brushless direct-current (BLDC) motor is widely regarded as a promising and versatile electronically controlled motor. Ensuring its reliable operation is crucial for maintaining production efficiency and safety.
Yi Ren, Runfei Yi, Zhaoxin Lian, Quan Xia, Dezhen Yang, Bo Sun, Qiang Feng   +6 more
doaj   +1 more source

Improving the Reliability and Utility of Streptozotocin-Induced Rat Diabetic Model [PDF]

, 2018
Yanlin Wang-Fischer, Tina Garyantes
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Shape-position perceptive fusion electronic skin with autonomous learning for gesture interaction

Microsystems & Nanoengineering
Wearable devices, such as data gloves and electronic skins, can perceive human instructions, behaviors and even emotions by tracking a hand's motion, with the help of knowledge learning.
Qian Wang, Mingming Li, Pingping Guo, Liang Gao, Ling Weng, Wenmei Huang   +5 more
doaj   +1 more source

The ESD Robustness and Protection Technology of P-GaN HEMT

Micromachines
This work first analyzes the failure behaviors of P-GaN HEMTs with different gate structures (Schottky gate vs. Ohmic gate) under both forward and reverse ESD stresses.
Yijun Shi, Yantao Chen, Liang He, Xinghuan Chen, Yuan Chen, Guoguang Lu   +5 more
doaj   +1 more source

A Machine-Learning-Based Prediction Method for Hypertension Outcomes Based on Medical Data

Diagnostics, 2019
The outcomes of hypertension refer to the death or serious complications (such as myocardial infarction or stroke) that may occur in patients with hypertension.
Wenbing Chang, Yinglai Liu, Yiyong Xiao, Xinglong Yuan, Xingxing Xu, Siyue Zhang, Shenghan Zhou   +6 more
doaj   +1 more source