Results 61 to 70 of about 4,984,516 (327)

Prediction of Hypertension Outcomes Based on Gain Sequence Forward Tabu Search Feature Selection and XGBoost

open access: yesDiagnostics, 2021
For patients with hypertension, serious complications, such as myocardial infarction, a common cause of heart failure, occurs in the late stage of hypertension. Hypertension outcomes can lead to complications, including death.
Wenbing Chang   +6 more
doaj   +1 more source

Application of a truncated normal failure distribution in reliability testing [PDF]

open access: yes, 1968
Statistical truncated normal distribution function is applied as a time-to-failure distribution function in equipment reliability estimations. Age-dependent characteristics of the truncated function provide a basis for formulating a system of high ...
Groves, C., Jr.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

General Stress-Strength Interference and Gamma Process Combined Method for Space Solar Cell Components Reliability Analysis

open access: yesIEEE Access, 2019
Space solar cell components always suffered from the complex and hostile space environment. The reliability of space solar cell components is important to ensure the mission success of space satellites.
Bo Sun   +6 more
doaj   +1 more source

Reliability approach for safe designing on a locking system [PDF]

open access: yes, 2010
The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe   +3 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Product and service reliability estimation [PDF]

open access: yesJournal of Engineering Management and Competitiveness, 2019
Some manufacturers in Europe neglect to determine the reliability of products and services, although reliability is a very significant magnitude of the quality of process results (semi-finished product, product, documentation, service).
Popović Branko Z.
doaj  

Engineering and Analytical Method for Estimating the Parametric Reliability of Products by a Low Number of Tests [PDF]

open access: gold, 2022
Alexey Amosov   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Skill Vehicle Routing Problem With Time Windows Considering Dynamic Service Times and Time-Skill-Dependent Costs

open access: yesIEEE Access, 2019
Service processes in modern logistic systems tend to be highly specialized and intellectualized. However, some casual and unexpected behavior may occur, causing specific dynamic interactions among their many constituents.
Xiaoyuan Yan   +5 more
doaj   +1 more source

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