Results 81 to 90 of about 4,984,516 (327)

The model and method of SCADA diagnostics as an object with partially defined parameters [PDF]

open access: yes, 2017
Modern SCADA are widely spread all over the world to control technological processes in different industries such as power engineering, military, transport, etc.
Syrotkina, O.
core   +4 more sources

Evaluation of software dependability [PDF]

open access: yes, 1996
It has been said that the term software engineering is an aspiration not a description. We would like to be able to claim that we engineer software, in the same sense that we engineer an aero-engine, but most of us would agree that this is not currently ...
Littlewood, B.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Metamodel-based importance sampling for the simulation of rare events

open access: yes, 2011
In the field of structural reliability, the Monte-Carlo estimator is considered as the reference probability estimator. However, it is still untractable for real engineering cases since it requires a high number of runs of the model.
Deheeger, F., Dubourg, V., Sudret, B.
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Mathematical techniques for estimating operational readiness of complex systems [PDF]

open access: yes, 1972
Development of methods for predicting operational readiness of complex systems based on probability theory is discussed. Operational readiness of systems is defined and mathematical relationships involved in determining readiness are presented.
Jacquier, I. D., Miltz, P. A.
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The Temperature Compensation of FBG Sensor for Monitoring the Stress on Hole-Edge

open access: yesIEEE Photonics Journal, 2018
To apply Fiber Bragg Grating (FBG) sensors in the hole structural health monitoring of aircraft, this study investigates a temperature compensation algorithm based on Fourier curve-fitting, combined with an analysis of FBG layout.
Feifei Ren   +5 more
doaj   +1 more source

Reliability Analysis of Concurrent Systems using LTSA [PDF]

open access: yes, 2007
The analysis for software dependability is considered an important task within the software engineering life cycle. However, it is often impossible to carry out this task due to the complexity of available tools, lack of expert personnel and time-to ...
Rodrigues, GN, Rosenblum, DS, Wolf, J
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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