Results 91 to 100 of about 5,939,353 (298)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

An explorative application of the task reliability index framework for human reliability data collection

open access: yes
To enhance the empirical basis of probability estimates of human failure events in human reliability analysis, a framework for data collection and analysis has recently been proposed based on a task reliability index (TRI).
Kim, Yochan (author)   +2 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

THE RELIABILITY INDEX APPROACH WITH EVOLUTIONARY ALGORITHMS: APPLICATION TO THE RBRDO PROBLEM OF COMPOSITE STRUCTURES

open access: yes, 2018
A new methodology to solve the Reliability Index Approach (RIA) minimization problem with high levels of accuracy and still with practical efficiency is presented.
Carlos Alberto Conceição António   +1 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The reliability of wind turbines [PDF]

open access: yes, 2008
The residual scepticism surrounding the installation of wind turbines, is mainly due to the perceived lack of reliability and expense of these energy converters. Because of the commercial significance of reliability, few sources of such data are publicly
Spinato, Fabio, Spinato, Fabio
core  

Safety Assessment of Existing Reinforced Concrete Structures According to the Standards of the Republic of Belarus

open access: yesЖелезобетонные конструкции
In the last decade, as part of the sustainable development strategy, more attention is paid to extending the service life of existing buildings and civil engineering structures.
D. N. Lazousky, V. V. Tur, D. O. Glukhov
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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