Results 101 to 110 of about 1,648,948 (305)

Reliability and Test Differences for the Impact: Implications for Concussion Testing Programs

, 2019
This study was conducted to determine the long-term relatability of ImPACT scores among young athletes. Youth sport participants (n=294) who completed ImPACT tests one year apart were included in the study.
Koch, Christopher, Robertson, Sean
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Safety Assessment of Existing Reinforced Concrete Structures According to the Standards of the Republic of Belarus

Железобетонные конструкции
In the last decade, as part of the sustainable development strategy, more attention is paid to extending the service life of existing buildings and civil engineering structures.
D. N. Lazousky, V. V. Tur, D. O. Glukhov
doaj   +1 more source

On the Importance of Coefficient Alpha for Measurement Research: Loading Equality Is Not Necessary for Alpha's Utility as a Scale Reliability Index. [PDF]

Educ Psychol Meas, 2023
Raykov T, Anthony JC, Menold N.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Probabilistic slope stability analysis on marine clay seabed considering spatial variability of soil parameters

Frontiers in Built Environment
Determining the failure probabilities of submarine slopes over long distances is crucial for assessing slope stability, given the randomness of soil parameters.
Long Yu, Yang Bao, Kunming Ma, Yunrui Han, Yibin Yan, Bin Xu, Zhongtao Wang, Rui Pang   +7 more
doaj   +1 more source

Studi Kehandalan Struktur Anjungan Lepas Pantai Tipe Brace Monopod [PDF]

, 2004
. API RP2A –LRFD standard was developed based on Gulf of Mexico environment. Therefore, application of the standard in Indonesia will result in an over designed structure since the environment in Indonesia is less severe compare to the environment in ...
Adriadi, R. (Ricky), Baskara, A. R. (Aria), Tawekal, R. L. (Ricky)   +2 more
core  

VsN, a Reliability-index of Shear-wave Measurement in Sonoelastography, Is Useful for the Diagnosis of Thyroid Tumor Malignancy. [PDF]

In Vivo, 2022
Jikuzono T, Ishibashi O, Kure S, Itoh C, Yamada T, Sugitani I.   +5 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source