Results 21 to 30 of about 34,432 (188)
BMC Infectious Diseases, 2023 Background Remdesivir is considered to be a specific drug for treating coronavirus disease 2019. This systematic review aims to evaluate the clinical efficacy and risk of remdesivir alone and in combination with other drugs.
Chuizhe Chen +6 more
doaj +1 more source
Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters
Pharmaceutics, 2021 Remdesivir has been approved for treatment of COVID-19 and shortens the time to recovery in hospitalized patients. Drug transporters removing remdesivir from the circulation may reduce efficacy of treatment by lowering its plasma levels.
Anne T. Nies +5 more
doaj +1 more source
Journal of Evaluation in Clinical Practice, Volume 29, Issue 1, Page 3-12, February 2023., 2023 Abstract Rationale, Aims and Objectives Critics have charged that evidence‐based medicine (EBM) overemphasises algorithmic rules over unstructured clinical experience and intuition, but the role of structured decision support systems in improving health outcomes remains uncertain.
Benjamin Djulbegovic +9 more
wiley +1 more source
Clinical and Translational Science, 2022 On October 2020, the US Food and Drug Administration (FDA) approved remdesivir as the first drug for the treatment of coronavirus disease 2019 (COVID‐19), increasing remdesivir prescriptions worldwide.
Se Yong Jung +30 more
doaj +1 more source
Trials, 2021 Background Remdesivir is a novel broad-spectrum antiviral therapeutic with activity against several viruses that cause emerging infectious diseases.
Stephen I. Walimbwa +5 more
doaj +1 more source
Viral load at hospitalization is an independent predictor of severe COVID‐19
, 2023 European Journal of Clinical Investigation, Volume 53, Issue 1, January 2023.
Hjalmar Waller +12 more
wiley +1 more source
Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction
Communications Biology, 2023 Remdesivir is an antiviral drug used for COVID-19 treatment worldwide. Cardiovascular side effects have been associated with remdesivir; however, the underlying molecular mechanism remains unknown.
Akiko Ogawa +10 more
doaj +1 more source
Prominent bradycardia in a COVID-19 patient receiving Remdesivir: a case report
Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2022 Remdesivir is a commonly used antiviral drug to treat COVID-19. Remdesivir has some side effects; however, whether it has any effect on cardiac is rarely reported.
Sidhi Laksono Purwowiyoto +1 more
doaj +1 more source
Remdesivir (GS-5734) Impedes Enterovirus Replication Through Viral RNA Synthesis Inhibition
Frontiers in Microbiology, 2020 Human enteroviruses are responsible for diverse diseases, from mild respiratory symptoms to fatal neurological complications. Currently, no registered antivirals have been approved for clinical therapy.
Wei Ye +16 more
doaj +1 more source
Pharmacology Research & Perspectives, 2021 Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID‐19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a broad range of molecules, including ...
Paul Biever +7 more
doaj +1 more source