Results 41 to 50 of about 49,641 (173)

An Analysis of Remdesivir Patenting [PDF]

open access: yes, 2020
Pharmaceutical patents are categorized into primary patents and secondary patents. Primary patents refer to compound patents, while secondary patents mainly include crystalline form patents, process patent, formulation patent and method of use patent. In
CHANG, Tingbin, WANG, Zhong
core   +2 more sources

Cost utility analysis of Remdesivir and Dexamethasone treatment for hospitalised COVID-19 patients - a hypothetical study [PDF]

open access: yes, 2021
Background: Sars-Cov-2 is a novel corona virus associated with significant morbidity and mortality. Remdesivir and Dexamethasone are two treatments that have shown to be effective against the Sars-Cov-2 associated disease.
Carta, A., Conversano, C.
core   +1 more source

Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction

open access: yesCommunications Biology, 2023
Remdesivir is an antiviral drug used for COVID-19 treatment worldwide. Cardiovascular side effects have been associated with remdesivir; however, the underlying molecular mechanism remains unknown.
Akiko Ogawa   +10 more
doaj   +1 more source

Comparative outcome analysis of hydroxychloroquine/chloroquine, remdesivir and standard of care treatment against COVID-19 infection [PDF]

open access: yes, 2020
This study aimed to compare the efficacy and safety of hydroxychloroquine/chloroquine (HCQ/CQ), remdesivir and standard of care treatment (SOC) in patients with nCoV-19 based on the RCTs available in the literature.
Kumar, Vikas, Mahato, Sumit Kumar
core   +2 more sources

Real-life experience with remdesivir for treatment of hospitalized coronavirus disease 2019 patients: matched case-control study from a large tertiary hospital registry [PDF]

open access: yes, 2022
Aim To evaluate the association of remdesivir use and the survival of hospitalized patients with coronavirus disease 2019 (COVID-19). Methods We retrospectively reviewed the medical re - cords of 5959 COVID-19 patients admitted to our ...
Babić, Paško   +13 more
core   +2 more sources

Prominent bradycardia in a COVID-19 patient receiving Remdesivir: a case report

open access: yesQanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2022
Remdesivir is a commonly used antiviral drug to treat COVID-19. Remdesivir has some side effects; however, whether it has any effect on cardiac is rarely reported.
Sidhi Laksono Purwowiyoto   +1 more
doaj   +1 more source

Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature [PDF]

open access: yes, 2020
In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is
Aly, Besma   +9 more
core  

Remdesivir (GS-5734) Impedes Enterovirus Replication Through Viral RNA Synthesis Inhibition

open access: yesFrontiers in Microbiology, 2020
Human enteroviruses are responsible for diverse diseases, from mild respiratory symptoms to fatal neurological complications. Currently, no registered antivirals have been approved for clinical therapy.
Wei Ye   +16 more
doaj   +1 more source

Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19

open access: yesPharmacology Research & Perspectives, 2021
Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID‐19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a broad range of molecules, including ...
Paul Biever   +7 more
doaj   +1 more source

Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing

open access: yesPharmaceutics, 2020
Remdesivir exhibits in vitro activity against SARS-CoV-2 and was granted approval for emergency use. To maximize delivery to the lungs, we formulated remdesivir as a dry powder for inhalation using thin film freezing (TFF).
Sawittree Sahakijpijarn   +4 more
doaj   +1 more source

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