Results 51 to 60 of about 46,545 (326)
Longitudinal Scalar-on-Function Regression with Application to Tractography Data [PDF]
, 2012 We propose a class of estimation techniques for scalar-on-function regression in longitudinal studies where both outcomes, such as test results on motor functions, and functional predictors, such as brain images, may be observed at multiple visits.
Crainiceanu, Ciprian +3 more
core +1 more source
Fixed and Random Effects Selection by REML and Pathwise Coordinate Optimization [PDF]
Journal of Computational and Graphical Statistics, 2013 We propose a two-stage model selection procedure for the linear mixed-effects models. The procedure consists of two steps: First, penalized restricted log-likelihood is used to select the random effects, and this is done by adopting a Newton-type algorithm.
Bingqing, Lin, Zhen, Pang, Jiming, Jiang
openaire +2 more sources
Advanced Science, EarlyView.A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra +23 more
wiley +1 more source
Trade-offs between personal immunity and reproduction in the burying beetle, N. vespilloides [PDF]
, 2014 We know that parental investment and immune investment are costly processes, but it is unclear which trait will be prioritised when both may be required.
Cotter, Sheena C. +3 more
core +2 more sources
REML estimation: asymptotic behavior and related topics
The Annals of Statistics, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
Advanced Science, EarlyView.This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
So near and yet so far: Harmonic radar reveals reduced homing ability of nosema infected honeybees [PDF]
, 2014 Pathogens may gain a fitness advantage through manipulation of the behaviour of their hosts. Likewise, host behavioural changes can be a defence mechanism, counteracting the impact of pathogens on host fitness.
Clark, Suzanne J. +6 more
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Natural orifice specimen extraction (NOSE) in colon cancer surgery raises concerns about intra‐abdominal infection, peritoneal seeding, and local recurrence due to possible tumor cell implantation. This systematic review and meta‐analysis compares complete intracorporeal resection with NOSE versus conventional laparoscopic colon ...
Daichi Kitaguchi +4 more
wiley +1 more source
Evaluation of Seed Yield Stability of Lentil Genotypes Based on REML/BLUP and Multi-Trait Stability Index (MTSI) [PDF]
پژوهشنامه اصلاح گیاهان زراعیExtended Abstract Background: Lentil is a popular legume crop in the Mediterranean region, widely grown for its nutritious seeds and improving soil fertility.
Payam Pezeshkpour +3 more
doaj
Information Splitting for Big Data Analytics
, 2016 Many statistical models require an estimation of unknown (co)-variance parameter(s) in a model. The estimation usually obtained by maximizing a log-likelihood which involves log determinant terms. In principle, one requires the \emph{observed information}
Gu, Tongxiang +3 more
core +1 more source