Results 41 to 50 of about 3,792 (227)

Cardiac Remote Conditioning and Clinical Relevance: All Together Now!

Engineering, 2015
Acute myocardial infarction (AMI) is the leading cause of death and disability worldwide. Timely reperfusion is the standard of care and results in decreased infarct size, improving patient survival and prognosis.
Kristin Luther, Yang Song, Yang Wang, Xiaoping Ren, W. Keith Jones   +4 more
doaj   +1 more source

Remote Ischemic Conditioning and Renal Protection

Journal of Cardiovascular Pharmacology and Therapeutics, 2017
Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures.
Giannopoulos, G., Vrachatis, D.A., Panagopoulou, V., Vavuranakis, M., Cleman, M.W., Deftereos, S.   +5 more
openaire   +3 more sources

Adenosine Receptor Activation in the “Trigger” Limb of Remote Pre-Conditioning Mediates Human Endothelial Conditioning and Release of Circulating Cardioprotective Factor(s)

JACC: Basic to Translational Science, 2016
Remote ischemic pre-conditioning (rIPC) has emerged as a potential mechanism to reduce ischemia-reperfusion injury. Clinical data, however, have been mixed, and its physiological basis remains unclear, although it appears to involve release of ...
Hussain Contractor, MBChB, DPhil, Rasmus Haarup Lie, MD, PhD, Colin Cunnington, MBChB, DPhil, Jing Li, PhD, Nicolaj B. Støttrup, MD, PhD, Cedric Manlhiot, BSc, Hans Erik Bøtker, MD, PhD, Michael R. Schmidt, MD, PhD, J. Colin Forfar, MD, PhD, Houman Ashrafian, MB BChir, DPhil, Andrew Redington, MBBS, PhD, Rajesh K. Kharbanda, MBChB, PhD   +11 more
doaj   +1 more source

Effects of remote ischemic conditioning on conditioned pain modulation and cardiac autonomic modulation in women with knee osteoarthritis: placebo-controlled randomized clinical trial protocol

Trials, 2023
Background It is estimated that over 240 million people worldwide have osteoarthritis, which is a major contributor to chronic pain and central changes in pain processing, including endogenous pain modulation. The autonomic nervous system plays a crucial
Taíse Mendes Biral, Allysiê Priscilla de Souza Cavina, Eduardo Pizzo Junior, Carlos Alberto Toledo Teixeira Filho, Franciele Marques Vanderlei   +4 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Remote ischemic conditioning: the enigmatic transfer of protection [PDF]

Cardiovascular Research, 2017
This editorial refers to ‘Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning’ by Basalay et al. , doi: 10.1093/cvr/cvw216. Remote ischemic conditioning is the systemic response to brief non-lethal ischemia/reperfusion in various tissues or organs which provides protection to a number of target tissues or organs
openaire   +3 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Rationale for ischemic conditioning to prevent stroke in patients with intracranial arterial stenosis

Brain Circulation, 2016
Intracranial atherosclerotic arterial stenosis (ICAS) is one of the most common causes of stroke worldwide and is associated with particularly a high risk of recurrent stroke.
Sami Al Kasab, David C Hess, Marc I Chimowitz   +2 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source