Results 231 to 240 of about 512,677 (302)

Bioinformatics analyses reveal the role of RIPK1 in clear cell renal cell carcinoma. [PDF]

BMC Cancer
Fang D, Hu Y, Sun S, Wen H, Fan J.
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Gut microbiome impact on systemic therapy outcomes in metastatic renal cell carcinoma: a systematic review. [PDF]

World J Urol
Gavi F, Bracco M, Testori N, Rossi F, Fettucciari D, Panio E, Assumma S, Russo P, Gandi C, Foschi N, Ragonese M, Turri F, Bientinesi R, Palermo G, Ciccarese C, Iacovelli R, Kröner PT, Gasbarrini A, Sighinolfi MC, Rocco B.   +19 more
europepmc   +1 more source

A summary of the status of de novo cancer in transplant recipients. [PDF]

, 1972
Penn, I, Starzl, TE
core  

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Soluble MAdCAM-1 as a biomarker in metastatic renal cell carcinoma. [PDF]

Nat Med
Alves Costa Silva C, Machaalani M, Saliby RM, Zhong C, Xie W, Pasolli E, Piccinno G, Dalban C, Fidelle M, Meurisse A, Vernerey D, Lee GM, Birebent R, Saad E, Steiner C, Flippot R, Barros-Monteiro J, Segata N, Thiery-Vuillemin A, Formenti S, Kuznetsova T, Escudier B, Derosa L, Zitvogel L, Choueiri TK, Albiges L.   +25 more
europepmc   +1 more source

Ultrasound–triggered tumor‐selective nitric oxide release enhances tumor penetration of antibody–conjugated nanomedicine

Interdisciplinary Medicine, EarlyView.
Ultrasound‐triggered nitric oxide release from S‐nitrosated hyaluronic acid (HA‐SNO) induces tumor vasodilation and disrupts the vascular barrier, potently enhancing the intratumoral penetration of antibody‐conjugated nanomedicines. Abstract The tumor vascular barrier restricts the penetration of antibody‐conjugated nanomedicine, severely limiting its ...
Xiaodong Wang, Ruifeng Duan, Xin Chen, Tongjun Liu, Zhilin Liu   +4 more
wiley   +1 more source

Early-Onset Bilateral Clear Cell Renal Cell Carcinoma in a Pediatric Renal Transplant Recipient: A Rare Case Report. [PDF]

Case Rep Urol
Gautam RK, Adhikari MB, Khadga A, Maharjan B, Shrestha PP, Mishra P, Yadav DK, Basnet B, Ghimire S, Parmar AS.   +9 more
europepmc   +1 more source

Metastatic Renal Cell Carcinoma Detected by Postprandial Abdominal Pain: A Case Report. [PDF]

Cancer Rep (Hoboken)
Wang X, Zhang N, Zeng S.
europepmc   +1 more source