Results 241 to 250 of about 357,421 (301)

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Sarcomatoid Renal Cell Carcinoma: Biological Features and Therapeutic Implications-A Narrative Review. [PDF]

Curr Urol Rep
Lasorsa F, Milella M, Rutigliano M, di Bari A, d'Amati A, Pandolfo SD, Bignante G, Caniglia A, Autorino R, Ditonno P, Lucarelli G.   +10 more
europepmc   +1 more source

Isolated pulmonary lymphangitic carcinomatosis as the initial manifestation of renal cell carcinoma. [PDF]

Radiol Case Rep
Liu S, Ku M, Bajantri B.
europepmc   +1 more source

Epithelial-Mesenchymal Transition Markers in Clear Cell Renal Cell Carcinoma: Expression Patterns and Prognostic Significance. [PDF]

J Pers Med
Smoljo L, Mateljak T, Racetin A, Todorović P, Komić J, Komić L, Đolonga P, Grubišić DA, Kostić S, Vukojević K, Kelam N.   +10 more
europepmc   +1 more source

Immune Escape in Renal Cell Carcinoma: Latest Research and Treatment Strategies. [PDF]

Int J Mol Sci
Huang K, Chen K.
europepmc   +1 more source

Characterization of aberrant alternative splicing landscape in patients with metastatic renal cell carcinoma. [PDF]

J Immunother Cancer
Govindarajan A, Hansen N, Mercier BD, Byron SA, Hegde A, Garcia-Mansfield K, Leskoske K, Chawla N, Meza L, Zengin Z, Barragan-Carillo R, Ebrahimi H, Castro DV, Dizman N, Hsu J, Chehrazi-Raffle A, Tripathi A, Salgia NJ, Pal SK, Pirrotte P.   +19 more
europepmc   +1 more source