Results 191 to 200 of about 457,723 (363)

RENAL REPLACEMENT THERAPY (RRT) AND ORTHOTOPIC LIVER TRANSPLANTATION(OLTX): A NEGATIVE PREDICTOR OF SURVIVAL.

open access: bronze, 2000
Thomas A. Gonwa   +5 more
openalex   +1 more source

Podocyte RIPK3 Deletion Improves Diabetic Kidney Disease by Attenuating NF‐κB p65 Driven Inflammation

open access: yesAdvanced Science, EarlyView.
Prevention and treatment of diabetic kidney disease (DKD) have become a major global public health challenge. This study shed new light on the underlying pathogenic mechanisms of podocyte injury in DKD and highlights the therapeutic potential of mitigating podocyte injury through inhibition of the RIPK3/NF‐κB p65‐mediated inflammatory response as a ...
Lu'an Li   +10 more
wiley   +1 more source

The first international consensus conference on continuous renal replacement therapy [PDF]

open access: bronze, 2002
John A. Kellum   +4 more
openalex   +1 more source

LncDARS‐AS1 Regulates ATP1A1 Stability and Enhances Na+/K+ ATPase Activity to Promote Osteosarcoma Metastasis

open access: yesAdvanced Science, EarlyView.
This study identifies LncDARS‐AS1 as a novel oncogenic regulator that stabilizes ATP1A1 and enhances Na⁺/K⁺ ATPase activity, promoting osteosarcoma metastasis. Targeting the LncDARS‐AS1/ATP1A1/NKA axis, including pharmacological inhibition with digoxin, offers promising opportunities for the development of new therapeutic strategies against ...
Mingxian Xu   +12 more
wiley   +1 more source

Outcomes of Kidney Transplantation From Donors on Renal Replacement Therapy. [PDF]

open access: yesTransplant Direct
Goussous N   +7 more
europepmc   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

open access: yesAdvanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang   +9 more
wiley   +1 more source

Continuous Renal Replacement Therapy in Critically-Ill Term and Preterm Newborns: A Single-Center Study in Belgrade. [PDF]

open access: yesChildren (Basel)
Rsovac S   +12 more
europepmc   +1 more source

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