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Inherited tubular renal acidosis
Annales de biologie clinique, 2011Renal tubular acidosis (RTA) is a tubulopathy characterized by metabolic acidosis with normal anion gap secondary to abnormalities of renal acidification. RTA can be classified into four main subtypes: distal RTA, proximal RTA, combined proximal and distal RTA, and hyperkalemic RTA.
Hassan, Bouzidi +4 more
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Current Opinion in Pediatrics, 2004
Research in the past several years has led to the understanding of numerous genetic mutations that lead to inheritable forms of distal renal tubular acidosis (dRTA). Most of these mutations affect the physiology of the A-intercalated cells of the renal cortical collecting duct.
Julie A, Nicoletta, George J, Schwartz
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Research in the past several years has led to the understanding of numerous genetic mutations that lead to inheritable forms of distal renal tubular acidosis (dRTA). Most of these mutations affect the physiology of the A-intercalated cells of the renal cortical collecting duct.
Julie A, Nicoletta, George J, Schwartz
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FAMILIAL RENAL TUBULAR ACIDOSIS
Annals of Internal Medicine, 1968Excerpt To the Editor:I was interested to read the editorial note on familial renal tubular acidosis (RTA) by Dr. Vardaman M. Buckalew (Ann. Intern. Med. 68: 1367, 1968).
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FAMILIAL RENAL TUBULAR ACIDOSIS
Annals of Internal Medicine, 1961Excerpt Acidosis of renal origin is an increased hydrogen ion concentration due to an impairment in the excretion of titratable acid and/or ammonium ion, to an excessive excretion of bicarbonate, o...
R E, RANDALL, W H, TARGGART
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Inherited renal tubular acidosis
Current Opinion in Nephrology and Hypertension, 2000The past few years have witnessed great progress in elucidating the molecular basis of inherited renal tubular acidosis. Consistent with the physiologically defined importance of multiple gene products in urinary acidification, heritable renal tubular acidosis is genetically heterogeneous.
C, Shayakul, S L, Alper
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Renal Tubular Acidosis in Leprosy
Annals of Internal Medicine, 1971Excerpt To the editor: Dr. Talal's comments regarding the relationship of renal tubular acidosis to peritubular infiltration of lymphocytes (1) are of particular interest to us because of studies w...
D J, Drutz, R A, Gutman
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Familial renal tubular acidosis
Journal of Nephrology, 2010Abstract The kidney maintains systemic acid–base homeostasis through proximal tubular reclamation of filtered bicar bonate, and excretion of the daily mineral acid load by collecting duct type A intercalated cells. Impairment of either process produces renal tubular acidosis (RTA).
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A review of renal tubular acidosis
Journal of Veterinary Emergency and Critical CareAbstractObjectiveTo review the current scientific literature on renal tubular acidosis (RTA) in people and small animals, focusing on diseases in veterinary medicine that result in secondary RTA.Data SourcesScientific reviews and original research publications on people and small animals focusing on RTA.SummaryRTA is characterized by defective renal ...
Manju Gauri Kunchur +3 more
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Understanding renal tubular acidosis
British Journal of Hospital MedicineRenal tubular acidosis is a group of disorders characterised by metabolic acidosis, hyperchloraemia, normal anion gap, and potassium imbalance. Genetic mutations, drugs or acquired disorders disrupt the function of various transport proteins and enzymes in the renal tubules, causing diminished bicarbonate reabsorption or inability to excrete hydrogen ...
Samuel Sherng Young, Wang +6 more
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