Results 81 to 90 of about 105,535 (331)
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
SHADER METAMODEL AS A COMPONENT OF AN INTERACTIVE APPLICATION ARCHITECTURE
This article introduces the rendering metamodel as an architecture basis for complicated graphi-cal applications. The model separates abstract logical and algorithmic approaches used in modern computer graphics theory from problems of computational ...
V. Kazantsava +2 more
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A Sort-Last Rendering System over an Optical Backplane [PDF]
Sort-Last is a computer graphics technique for rendering extremely large data sets on clusters of computers. Sort-Last works by dividing the data set into even-sized chunks for parallel rendering and then composing the images to form the final result ...
Yasuhiro Kirihata +3 more
doaj
Network based medical data computing and collaborative visualization have been commonly used in remote medicine and distributed diagnosis, where visualizing 3D medical data on web browsers and sharing medical information on internet are critically ...
Qi Zhang
doaj +1 more source
Light field image processing : overview and research issues [PDF]
Light field (LF) imaging first appeared in the computer graphics community with the goal of photorealistic 3D rendering [1]. Motivated by a variety of potential applications in various domains (e.g., computational photography, augmented reality, light ...
Farrugia, Reuben A. +1 more
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
A biophysical-based skin model for heterogeneous volume rendering
Realistic human skin rendering has been a long-standing challenge in computer graphics. Recently, biophysical-based skin rendering has received increasing attention, as it provides a more realistic skin-rendering and a more intuitive way to adjust the ...
Qi Wang +5 more
doaj +1 more source
Path tracing is a commonly used but computationally highly expensive stochastic ray tracing method for rendering photorealistic visual content. Combined with a real-time constraint, for example in stereoscopic virtual/augmented reality applications, it ...
Markku J. Makitalo +2 more
doaj +1 more source

