Results 121 to 130 of about 18,284,607 (258)

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli, Henryata E. Rozario, Victor Martinez, Zachary L. McAdams, Stephen A. Adkins, Aaron C. Ericsson, Yagna P. R. Jarajapu   +6 more
wiley   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

The balance between classical and alternative renin-angiotensin system in ARDS: a narrative review. [PDF]

J Intensive Care
Dragoni C, Sbaraini Zernini I, Calabrese A, Bianchi V, Spadaro S, Scaramuzzo G, Scolletta S, Taccone FS, Annoni F.   +8 more
europepmc   +1 more source

Risk Factors for Implant Failure and Peri‐Implantitis: A Retrospective Cohort Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This retrospective cohort study evaluated patient‐, implant‐, site‐, procedural‐, biological‐, and prosthesis/mechanics‐related factors associated with early and late implant failure and peri‐implantitis. Material and Methods Electronic health record data from a university center were analyzed.
Nathalia Vilela, Bruno C. V. Gurgel, Hélio D. P. da Silva, Claudio M. Pannuti, Poliana M. Duarte   +4 more
wiley   +1 more source

Renin-angiotensin system inhibitors (RASi) are not nephrotoxic - they protect the kidneys and the heart. [PDF]

Clin Med (Lond)
Murray JS, Kalra PR, Anderson LJ, Selby NM, Sawhney S, McKane WS, Ostermann M, Kolhe NV, McWilliam SJ, Nagalingam K, Bickerton S, Lewington AJP, Hinchliffe WT, Smith SJ, Wise M, Hancock A, Kingdon E, Cockwell P, James MT, Blakeman T, Dean JD, Morlidge C, Tomlinson LA, Green D.   +23 more
europepmc   +1 more source

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

Cell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang, Wenjie Chen, Jingjing Ke, Hongtu Hu, Zhuan Peng, Yue Qi, Guohua Ding, Jijia Hu   +7 more
wiley   +1 more source

NOMENCLATURE OF THE RENIN-ANGIOTENSIN SYSTEM

Japanese Circulation Journal, 1978
openaire   +6 more sources

The relationship between renin-angiotensin system-modulating medication and depression: a systematic review. [PDF]

Transl Psychiatry
Kulkarni S, Prasad D, Bauermeister S, Reinecke A.   +3 more
europepmc   +1 more source