Results 101 to 110 of about 18,284,607 (258)

Known structures of the renin-angiotensin system.

, 2016
Known structures of the renin-angiotensin system.
Amy Milsted (30880), Robson A. S. Santos (384592), Jeremy W. Prokop (417645)   +2 more
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Astragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6‐Mediated Deacetylation

Phytotherapy Research, EarlyView.
AS‐IV binds to SIRT6 and promotes H3K9 deacetylation at the Notch1 promoter, inhibiting gene transcription (Created with BioGDP.com). ABSTRACT Astragaloside IV (AS‐IV) has demonstrated efficacy in ameliorating proteinuria and attenuating renal tubular damage in preclinical diabetic nephropathy (DN) models.
Qiyu Yue, Chen Yong, Xinran Wang, Yang Shu, Min Yao, Yongfei Yu, Yubai Xue, Rong Deng, Tianlu Chu, Weiwei Tao, Min Zhao, Enchao Zhou   +11 more
wiley   +1 more source

Butein Attenuates Cardiac Hypertrophy by Restoring Redox–Mitochondrial Homeostasis Through Nrf2–Sirt3 Signaling

Phytotherapy Research, EarlyView.
Butein attenuates pathological cardiac hypertrophy by activating Nrf2–Sirt3 signaling, restoring mitochondrial function and redox homeostasis. ABSTRACT Butein (3,4,2′,4′‐tetrahydroxychalcone) is a bioactive chalcone with antioxidant, anti‐inflammatory, and cytoprotective properties.
Tsendsuren Tungalag, Dong Kwon Yang
wiley   +1 more source

Ventilatory compensation for metabolic acidosis is independent of hypertension in dogs with chronic kidney disease

Veterinary Record, EarlyView.
Abstract Introduction Metabolic acidosis is common in dogs with chronic kidney disease (CKD) and induces ventilatory compensation. Systemic arterial hypertension frequently accompanies CKD, but its influence on the ventilatory response remains unclear.
Letícia da Silva Rueda, André Leal Raymundo Pessina, Igor Luiz Salardani Senhorello, Rodrigo Prevedello Franco, Paulo Sérgio Patto dos Santos, Maria Vitoria Magalhães Dias, Lucas Ferreira Gomes, Wagner Luis Ferreira   +7 more
wiley   +1 more source

Alternative renin-angiotensin system

The renin-angiotensin system is the most important peptide hormone system in the regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin, and angiotensin-converting enzyme, generating angiotensin II from angiotensinogen,
Alenina, N., Bader, Michael, Ferrario, Carlos M, Muscha Steckelings, U., Santos, R.A.S., Alenina, Natalia, Ferrario, C.M., Santos, Robson A S, Bader, M., Steckelings, U Muscha; id_orcid   +9 more
core   +1 more source

Influencing Factors Associated With Infantile Hemangioma: A Case–Control Study Among Chinese Pediatric Populations

The Journal of Dermatology, EarlyView.
ABSTRACT Infantile hemangioma (IH) is the most common benign vascular tumor of infancy. While its epidemiology is well‐documented in Caucasian populations, large‐scale systematic studies regarding clinical characteristics and risk factors in the Chinese population remain limited.
Xinyu Liu, Dan Song, Liang Wang, Changfeng Wang, Lei Guo   +4 more
wiley   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

The renin-angiotensin system (RAS)

, 2020
The renin-angiotensin system (RAS) was initially considered as a circulating humoral system, which function is the regulation of blood pressure and sodium and water homeostasis.
Ana I Rodríguez-Perez, Maria J Guerra, Rita Valenzuela, Begoña Villar-Cheda, Jose L Labandeira-Garcia, Jannette Rodriguez-Pallares, Pablo Garrido-Gil   +6 more
core  

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source