Results 151 to 160 of about 98,067 (262)

Influence of menstrual cycle phase on inflammatory and vascular responses to acute passive heating in healthy young women

Experimental Physiology, EarlyView.
Abstract The aim of this study was to determine whether inflammatory and vascular responses to passive heating differ between the early follicular phase (EFP) and the mid‐luteal phase (MLP) of the menstrual cycle. Ten healthy, naturally menstruating females (26 ± 3 years of age; body mass index 21.4 ± 1.9 kg/m2) were assessed during EFP and MLP ...
Yunuo Su, Emma O'Donnell, Stephen J. Bailey, Christof A. Leicht   +3 more
wiley   +1 more source

Impact of concomitant use of renin-angiotensin system inhibitors on survival in patients with pancreatic ductal adenocarcinoma: a systematic review and meta-analysis. [PDF]

Ther Adv Med Oncol
Kraj L, Chmiel P, Skrobucha A, Grabowska H, Szymański Ł, Wysocki PT, Peller M.   +6 more
europepmc   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Early administration of renin-angiotensin system inhibitors improves survival and cardiac remodeling in heart failure with preserved ejection fraction. [PDF]

PLoS One
Kono Y, Sonoda K, Ohtake K, Ota A, Yamamoto S, Nakayama H, Fukuoka T, Kawai Y, Tago H, Watanabe N, Sato I, Hirohata S, Kitamori K, Watanabe S.   +13 more
europepmc   +1 more source

Impact of recurrent dehydration with mild periodic water restriction on blood pressure and renal function in male spontaneously hypertensive rats

Experimental Physiology, EarlyView.
Abstract The kidneys regulate fluid balance but are susceptible to adverse effects of inadequate hydration. Epidemiological studies have linked low water intake to renal dysfunction and chronic kidney disease. Previously we showed that restricting water intake to a single 2‐h period daily for 4 weeks promotes hypertension as well as renal inflammation,
Katrina M. Mirabito Colafella, Peter N. H. Nguyen, Zoe McArdle, Debra Fong, Edmund Kwok, Kate M. Denton, Antony Vinh, Lucinda M. Hilliard Krause   +7 more
wiley   +1 more source

Impacts of exercise, renin-angiotensin system modulation or both on skeletal muscle circadian gene expression. [PDF]

Exp Physiol
Zumbro EL, Baptista LC, Taylor T, Hernandez AR, Banerjee A, Sun Y, Yang Y, Li Q, Buford TW.   +8 more
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Loss of the liver circadian clock affects the expression of intrarenal renin-angiotensin system components. [PDF]

Sci Rep
Hassan SA, Stumpe M, Hui KY, Giraud MN, Albrecht U, Ripperger JA.   +5 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Gut microbiota dysbiosis affects the local renin-angiotensin system to induce osteoporosis. [PDF]

Front Endocrinol (Lausanne)
Zhong K, Wang Y, Han P, Huang Z, Xie Z, Yu P, Liu H, Hu H, Tan M, Guo X.   +9 more
europepmc   +1 more source