Results 171 to 180 of about 18,284,607 (258)

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa   +13 more
wiley   +1 more source

Discharge Prescription of Renin-Angiotensin System Inhibitors After Hyperkalemia and Its Association With Mortality and Dialysis Outcomes. [PDF]

open access: yesCureus
Weiss Y   +6 more
europepmc   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan   +5 more
wiley   +1 more source

High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Introduction Fluid restriction is the current first‐line therapy for hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD), yet up to 50% of patients do not achieve an adequate plasma sodium correction. Reported predictors of nonresponse include urine osmolality >500 mOsm/kg, the Furst ratio >1 [(UNa + UK)/(PNa)], urine ...
Michelle Patricia Müller   +5 more
wiley   +1 more source

Physiopathology of the Brain Renin-Angiotensin System. [PDF]

open access: yesLife (Basel)
Cueto-Ureña C   +3 more
europepmc   +1 more source

The Goldilocks Principle in Neonatal Fluids: Finding the Just‐Right Balance

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT The impact of disrupted fluid balance on outcomes in critically unwell children and adults is well described. Recent literature in neonates has demonstrated that both fluid overload and excessive postnatal fluid losses are associated with increased morbidity and mortality.
Jane B. McMahon   +7 more
wiley   +1 more source

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