Results 1 to 10 of about 9,161 (86)

Importance of Hypercortisolism in BP Control, Cardiovascular Risk and in Patients With Difficult‐to‐Control Hypertension: An Overview for Primary Care Physicians

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Hypertension remains one of the most prevalent and consequential modifiable cardiovascular risk factors worldwide, affecting approximately 1.28 billion adults globally and nearly half of the United States population. Despite the availability of effective therapies, optimal blood pressure control is achieved in fewer than one in four ...
Matthew A. Cavender
wiley   +1 more source

High level of patient satisfaction with incremental haemodialysis: insights from a single‐centre patient‐reported experience study

open access: yesInternal Medicine Journal, Volume 56, Issue 8, Page 1438-1442, August 2026.
Abstract A single‐centre, anonymous survey study was conducted to investigate patient experience and quality of life (Kidney Disease Quality of Life‐36) in individuals receiving incremental haemodialysis, with all 20 eligible patients participating.
Kavita L. Dilip   +2 more
wiley   +1 more source

Ambulatory Blood Pressure Characteristics and Target Organ Effects in Hypertensive Children With Renal Artery Variations

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 8, August 2026.
ABSTRACT Renal artery variations are recognized as potential contributors to hypertension through altered renal perfusion and activation of renin–angiotensin system. However, their clinical and hemodynamic significance in children remains unclear. This retrospective study included 14 pediatric patients (0–18 years) with hypertension and renal artery ...
Mehmet Baha Aytac   +7 more
wiley   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Temporal Trends and Disparities in Hypertension‐Related Cardiomyopathy Mortality in the United States, 1999–2023

open access: yesClinical Cardiology, Volume 49, Issue 7, July 2026.
Hypertension‐related cardiomyopathy mortality in the United States increased sharply in 1999–2001 before declining through 2023. Persistent disparities by sex, race, geography, and age highlight the need for improved hypertension control, early cardiomyopathy management, and equitable access to cardiovascular care.
Javeria Akhter   +4 more
wiley   +1 more source

Takayasu Arteritis and Giant Cell Arteritis: Results From a Cross‐Sectional Study of 96 Italian Patients

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 7, July 2026.
Comparison of epidemiologic, clinical, laboratory, imaging, and treatment response features in 59 patients with Takayasu Arteritis (TAK) and 37 with Giant Cell Arteritis (GCA, 7 C‐GCA, 30 LV‐GCA) at diagnosis and during follow‐up demonstrates that these are distinct diseases, warranting disease‐specific diagnostic and therapeutic approaches.
Marcella Prete   +13 more
wiley   +1 more source

Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT In young patients with hypertension or stroke, the presence of bilateral parvus et tardus waveforms in the renal arteries should prompt reverse tracing to rule out aortic coarctation. This simple ultrasound clue enables early, non‐invasive screening and prevents missed diagnoses.
Yan‐li Chen, Jin‐hua Wang
wiley   +1 more source

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3399-3414, June 2026.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory   +3 more
wiley   +1 more source

Statin Therapy Protects White Matter in Cerebral Small Vessel Disease Independent of Lipid‐Lowering: Biomarker and Neuroimaging Evidence

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
This study, through an analysis of neuroimaging markers, biomarkers of white matter damage, and the volume of the hippocampal fimbria (a white matter structure) in patients with cerebral small vessel disease (CSVD), revealed that the protective effect of statin therapy against white matter damage in CSVD patients is independent of its lipid‐lowering ...
Rui Wang   +5 more
wiley   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay   +2 more
wiley   +1 more source

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