Results 71 to 80 of about 3,009,431 (281)
, 2016 This paper reports on EPSRC-funded research that explores the role of repair in creating new models of sustainable business. In the lifecycle stage of repair we explore what 'broken' means and uncover the nature of local and dispersed repair activities ...
Charter, M. +6 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Squamous Cell Carcinoma of the Bulbar Urethra Accompanied by Lichen Sclerosus: A Case Report
American Journal of Men's Health, 2018 Squamous cell carcinoma (SCC) of the bulbar urethra accompanied by lichen sclerosus (LS) is rarely reported. This study reports the case of a 56-year-old man with urethral squamous cell carcinoma (USCC) accompanied by a long history of genital LS.
Xufeng Peng +4 more
doaj +1 more source
Warranty Cost Analysis with an Alternating Geometric Process
, 2018 In this study we model the warranty claims process and evaluate the warranty servicing costs under non-renewing and renewing free repair warranties. We assume that the repair time for rectifying the claims is non-zero and the repair cost is a function of
Arnold, Richard +3 more
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
AerospaceThe aviation industry relies on continuous inspections to ensure infrastructure safety, particularly in confined spaces like aircraft fuel tanks, where human inspections are labor-intensive, risky, and expose workers to hazardous exposures.
Adrián Ricárdez Ortigosa +6 more
doaj +1 more source
Storage codes -- coding rate and repair locality [PDF]
, 2013 The {\em repair locality} of a distributed storage code is the maximum number of nodes that ever needs to be contacted during the repair of a failed node.
Hollmann, Henk D. L.
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Repair Locality From a Combinatorial Perspective
, 2014 Repair locality is a desirable property for erasure codes in distributed storage systems. Recently, different structures of local repair groups have been proposed in the definitions of repair locality.
Wang, Anyu, Zhang, Zhifang
core +1 more source