Results 1 to 10 of about 206,786 (119)

Transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells Attenuates Surgical Wound-Induced Blood-Brain Barrier Dysfunction in Mice

Stem Cells International, 2023
Blood-brain barrier (BBB) is the most important component of central nervous system (CNS) to keep toxins and pathogens from CNS. Although our studies demonstrated that using interleukin-6 antibodies (IL-6-AB) reversed the increased permeability of BBB ...
Jie Yang, Hongyu Li, Mingzi Ran, Shuxu Yang, Kui Ma, Cuiping Zhang, Minglu Xiao, Yuguang Yang, Xiaobing Fu, Siming Yang   +9 more
doaj   +1 more source

Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions

Cell Death and Disease, 2021
Persistent neutrophilic inflammation drives host damage in autoimmune diseases that are characterized by abundant immune complexes. Insoluble immune complexes (iICs) potently activate pro-inflammatory neutrophil effector functions.
Utsa Karmakar, Julia Y. Chu, Kruthika Sundaram, Anne L. Astier, Hannah Garside, Carsten G. Hansen, Ian Dransfield, Sonja Vermeren   +7 more
doaj   +1 more source

Effects of exosomes derived from placental mesenchymal stem cells on high glucose-induced senescence in human dermal fibroblasts

Di-san junyi daxue xuebao, 2020
Objective To explore the optimal conditions for inducing senescence in human dermal fibroblasts (HDFs) cultured in high glucose and observe the effect of exosomes derived from human placental mesenchymal stem cells (PMSCs) on the proliferation, migration
BIAN Xiaowei, BIAN Xiaowei, ZHANG Cuiping, LI Bingmin, MA Kui, YANG Jie, FU Xiaobing   +6 more
doaj   +1 more source

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

Signal Transduction and Targeted Therapy, 2023
The ageing process is a systemic decline from cellular dysfunction to organ degeneration, with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells or organisms more youthful characteristics through various techniques ...
Shuaifei Ji, Mingchen Xiong, Huating Chen, Yiqiong Liu, Laixian Zhou, Yiyue Hong, Mengyang Wang, Chunming Wang, Xiaobing Fu, Xiaoyan Sun   +9 more
doaj   +1 more source

Redirecting differentiation of mammary progenitor cells by 3D bioprinted sweat gland microenvironment

Burns & Trauma, 2019
Background Mammary progenitor cells (MPCs) maintain their reproductive potency through life, and their specific microenvironments exert a deterministic control over these cells.
Rui Wang, Yihui Wang, Bin Yao, Tian Hu, Zhao Li, Yufan Liu, Xiaoli Cui, Liuhanghang Cheng, Wei Song, Sha Huang, Xiaobing Fu   +10 more
doaj   +1 more source

Functional hair follicle regeneration: an updated review

Signal Transduction and Targeted Therapy, 2021
The hair follicle (HF) is a highly conserved sensory organ associated with the immune response against pathogens, thermoregulation, sebum production, angiogenesis, neurogenesis and wound healing. Although recent advances in lineage-tracing techniques and
Shuaifei Ji, Ziying Zhu, Xiaoyan Sun, Xiaobing Fu   +3 more
doaj   +1 more source

The role of multiomics in revealing the mechanism of skin repair and regeneration [PDF]

Frontiers in Pharmacology
Ou Xuehai, Shi Shaoyan, Xu Siqi
exaly   +2 more sources

Pleiotropic Roles of CXCR4 in Wound Repair and Regeneration

Frontiers in Immunology, 2021
Wound healing is a multi-step process that includes multiple cellular events such as cell proliferation, cell adhesion, and chemotactic response as well as cell apoptosis.
Huating Chen, Huating Chen, Gongchi Li, Yiqiong Liu, Shuaifei Ji, Yan Li, Yan Li, Jiangbing Xiang, Jiangbing Xiang, Laixian Zhou, Huanhuan Gao, Wenwen Zhang, Xiaoyan Sun, Xiaobing Fu, Binghui Li   +14 more
doaj   +1 more source

Development of a nomogram model for prediction of new adjacent vertebral compression fractures after vertebroplasty

BMC Surgery, 2023
Background Vertebroplasty is the main minimally invasive operation for osteoporotic vertebral compression fracture (OVCF), which has the advantages of rapid pain relief and shorter recovery time. However, new adjacent vertebral compression fracture (AVCF)
Yadong Qian, Xiao Hu, Chen Li, Jingwei Zhao, Yanjing Zhu, Yan Yu, Ning Xie, Bin Ma, Zhili Zeng, Liming Cheng   +9 more
doaj   +1 more source

Irf6 directs glandular lineage differentiation of epidermal progenitors and promotes limited sweat gland regeneration in a mouse burn model

Stem Cell Research & Therapy, 2018
Background Damaged or malfunctioning sweat glands (SGs) after a burn injury would cause significant hyperthermia and even death, and there is an unmet need for effective treatment.
Bin Yao, Wei Song, Zhao Li, Tian Hu, Rui Wang, Yihui Wang, Sha Huang, Xiaobing Fu   +7 more
doaj   +1 more source