The Cross-Talk between Mesenchymal Stem Cells and Immune Cells in Tissue Repair and Regeneration [PDF]
, 2021 Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory properties and, in juxtacrine and paracrine manner, modulate phenotype and
Djonov, Valentin +5 more
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c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]
, 2012 The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy +35 more
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Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]
, 2009 PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
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Human airway xenograft models of epithelial cell regeneration [PDF]
, 2000 Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory diseases such as chronic bronchitis, asthma and cystic fibrosis.
Puchelle Edith +5 more
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Non-stem Cell Mediated Tissue Regeneration and Repair
, 2023 Regrowth and replacement are two basic responses of the body to any injury. While regrowth is generally attributed to stem cells, and replacement or scarring to non-stem cells, there is much more to the repair process than that.
Reshamwala, Ronak +2 more
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The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
, 2013 Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Boomkamp, S.D. +13 more
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PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior [PDF]
, 2014 The benefits of exercise on wellbeing have been known to mankind for thousands of years, yet the underlying mechanisms of exercise have been explained only relatively recently.
Dinulović, Ivana
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Self-repair ability of evolved self-assembling systems in cellular automata [PDF]
, 2014 Self-repairing systems are those that are able to reconfigure themselves following disruptions to bring them back into a defined normal state. In this paper we explore the self-repair ability of some cellular automata-like systems, which differ from ...
Johnson, Colin G., Öztürkeri, Can
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Small molecules facilitate single factor-mediated sweat gland cell reprogramming
Military Medical Research, 2022 Background Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogramming strategy to convert fibroblasts
Shuai-Fei Ji +10 more
doaj +1 more source
TET knockout cells transit between pluripotent states and exhibit precocious germline entry
The EMBO JournalTET1, TET2 and TET3 are DNA demethylases with important roles in development and differentiation. To assess the contributions of TET proteins to cell function during early development, single and compound knockouts of Tet genes in mouse pluripotent ...
Raphaël Pantier +7 more
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