Results 41 to 50 of about 3,743,186 (287)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A multilevel meta-analysis of the effects of repeated sprint training in hypoxia on athletic performance

Frontiers in Sports and Active Living
BackgroundRepeated-sprint training in hypoxia (RSH) has emerged as a novel strategy to optimize repeated-sprint ability (RSA), aerobic capacity, and anaerobic performance in athletes.
Meng Han, Binglin Liu
doaj   +1 more source

The effect of repeated agility training vs. repeated sprint training on elite female soccer players' physical performance

Kinesiologia Slovenica, 2013
To compare the effects of repeated agility training along with repeated sprint training on elite female soccer players’ linear single sprint speed, vertical jump, agility, repeated sprint ability and Yo-Yo Intermittent Recovery level 1 test (Yo-Yo IR1 ...
Shaher A. I. Shalfawi, Marlene Young, Espen Tønnessen, Thomas A. Haugen, Eystein Enoksen   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hematological determinants of specific aerobic fitness and indices of repeated-sprint ability.

, 2016
Hematological determinants of specific aerobic fitness and indices of repeated-sprint ability.
Julien Rysman (834412), Grégoire P. Millet (379991), Thomas Steiner (378082), Franck Brocherie (834411), Jon P. Wehrlin (675953), Olivier Girard (409080), Anna Hauser (675952)   +6 more
core   +1 more source

Physiological Responses to Repeated Running Sprint Ability Tests: A Systematic Review [PDF]

, 2020
International Journal of Exercise Science 13(4): 1190-1205, 2020. The purpose of this study was to review acute physiological responses induced by repeated running sprint ability (RRSA) tests that could serve as references for practitioners utilising ...
Charron, Jérémie, Comtois, Alain Steve, Ferland, Pierre-Marc, Roy, Philippe, Veliz-Garcia, Juan Emmanuel   +4 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effect of change-of-direction vs. linear repeated sprint training on physical performance in female college basketball players

Scientific Reports
This study examined the effects of repeated sprint training (RST) with and without change of direction (COD) on physical performance in 30 trained female collegiate basketball players.
Yang Lin, Wei Zhang, Lei Zhao, Yi Yang
doaj   +1 more source