Results 61 to 70 of about 4,206,856 (305)

JMASM45: A Computer Program for Bayesian D-Optimal Binary Repeated Measurements Designs (Matlab) [PDF]

, 2017
Planners of longitudinal studies of binary responses in applied sciences have not yet benefitted from optimal designs, which have been shown to improve precision of model parameter estimates, due to absence of a computer program.
van Breukelen, Gerard J.P.; id_orcid, Berger, Martijn P.F., Berger, Martijn P. F., van Breukelen, Gerard J. P., Abebe, Haftom Temesgen, van Breukelen, Gerard J.P., Haftom Temesgen Abebe, Tan, Frans E. S., Frans E. S. Tan, Martijn P. F. Berger, Tan, Frans E.S., Gerard J. P. van Breukelen   +11 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

HE Plots for Repeated Measures Designs [PDF]

Hypothesis error (HE) plots, introduced in Friendly (2007), provide graphical methods to visualize hypothesis tests in multivariate linear models, by displaying hypothesis and error covariation as ellipsoids and providing visual representations of effect
Michael Friendly
core  

Optimal repeated measurements designs under interaction

, 1987
The robustness of some optimality results on repeated measurements designs is investigated when the underlying model is allowed to be non-additive incorporating an interaction due to the direct and residual effects of treatments.
Sen, Mausumi, Mukerjee, Rahul
core   +1 more source

Migration of all-polyethylene compared with metal-backed tibial components in cemented total knee arthroplasty: A randomized controlled trial

Acta Orthopaedica, 2018
Background and purpose — With a rapidly increasing population in need of total knee arthroplasty (TKA), there is renewed interest in cost-saving all-polyethylene designs.
Koen T Van Hamersveld, Perla J Marang-Van De Mheen, Rob G H H Nelissen, Sören Toksvig-Larsen   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The 1H NMR serum metabolomics response to a two meal challenge: a cross-over dietary intervention study in healthy human volunteers

Nutrition Journal, 2019
Background Metabolomics represents a powerful tool for exploring modulation of the human metabolome in response to food intake. However, the choice of multivariate statistical approach is not always evident, especially for complex experimental designs ...
Millie Rådjursöga, Helen M. Lindqvist, Anders Pedersen, Göran B. Karlsson, Daniel Malmodin, Carl Brunius, Lars Ellegård, Anna Winkvist   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Optimal designs for an interference model [PDF]

Kunert and Martin (2000) determined optimal and efficient block designs in a model for field trials with interference effects, for block sizes up to 4. In this paper we use Kushner's method (Kushner, 1997) of finding optimal approximate designs to extend
Kunert, Joachim, Mersmann, Sabine
core