Results 31 to 40 of about 432,839 (343)

Role of autophagy in hypoxia-reoxygenation-induced injury of rat alveolar epithelial cell type Ⅱ [PDF]

Jichu yixue yu linchuang, 2021
Objective To investigate the role of autophagy in the hypoxia-reoxygenation (H/R) model of rat alveolar epithelial cell type Ⅱ (AEC Ⅱ). Methods Cells were randomly divided into control group (C),hypoxia-reoxygenation group (H/R),solvent group
LIU Xiu-jie, WANG Xin-yun, SONG Zheng-yang, LOU Guo-qiang, HAO Mao-lin, QIAN Wei, WANG Wan-tie
doaj  

Recalibrating Reperfusion Waypoints [PDF]

Circulation, 2017
Article, see p 1462 > There falls a shadow, as T. S. Eliot noted, between the conception and the creation. In the annals of innovation, new ideas are only part of the equation. Execution is just as important . > > —Walter Isaacson ( Steve Jobs , p.
Paul W, Armstrong, Robert C, Welsh
openaire   +2 more sources

The pathological role of ferroptosis in ischemia/reperfusion-related injury

Zoological Research, 2020
Ischemia/reperfusion (I/R) is a pathological process that occurs in numerous organs throughout the human body, and it is frequently associated with severe cellular damage and death.
Hong-fa Yan, Qing-zhang Tuo, Q. Yin, P. Lei   +3 more
semanticscholar   +1 more source

Reperfusion and reperfusion injury after ischemic stroke

Environmental Disease, 2022
Objectives: Stroke is a leading cause of distress, disability, and death worldwide. The goal of reperfusion therapy for acute ischemic stroke (AIS) is the restoration of cerebral blood flow (CBF). If initiated too late, however, reperfusion therapy may paradoxically exacerbate tissue injury.
Jie Gao, Alexandra Wehbe, Fengwu Li, Naveed Chaudhry, Changya Peng, Xiaokun Geng, Yuchuan Ding   +6 more
openaire   +1 more source

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

Nature Communications, 2018
Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.
Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C. Norris, Nan Chiang, Charles N. Serhan   +7 more
doaj   +1 more source

Predictors of clinical outcomes after cardiac resynchronization therapy in patients ≥75 years of age: a retrospective cohort study

BMC Geriatrics, 2019
Background Cardiac resynchronization therapy has been shown to benefit selected patients with heart failure and reduced ejection fraction. Older patients have been underrepresented in randomized trials.
Laure Champ-Rigot, Anne-Laure Cornille, Pierre Ollitrault, Arnaud Pellissier, Mathieu Chequel, Damien Legallois, Paul Milliez   +6 more
doaj   +1 more source

Myostatin Deficiency Protects C2C12 Cells from Oxidative Stress by Inhibiting Intrinsic Activation of Apoptosis

Cells, 2021
Ischemia reperfusion (IR) injury remains an important topic in clinical medicine. While a multitude of prophylactic and therapeutic strategies have been proposed, recent studies have illuminated protective effects of myostatin inhibition. This study aims
Marius Drysch, Sonja Verena Schmidt, Mustafa Becerikli, Felix Reinkemeier, Stephanie Dittfeld, Johannes Maximilian Wagner, Mehran Dadras, Alexander Sogorski, Maxi von Glinski, Marcus Lehnhardt, Björn Behr, Christoph Wallner   +11 more
doaj   +1 more source

Left ventricular function assessment using 123I/99mTc dual-isotope acquisition with two semi-conductor cadmium–zinc–telluride (CZT) cameras: a gated cardiac phantom study

EJNMMI Physics, 2016
Background The impact of increased energy resolution of cadmium–zinc–telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions (99mTc and 123I) remains unknown. The Amsterdam-gated dynamic cardiac phantom (AGATE,
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini, Alain Manrique   +5 more
doaj   +1 more source

Is Biochemical Follow Up Possible in Peripheral Arterial Disease Treatment: Hypoxia Inducible Factor-1 Alpha?

Vascular Specialist International, 2021
Purpose: The hypoxia inducible factor (HIF)-1 is a dimeric protein complex that plays an integral role in the body’s response to hypoxia. This study aimed to analyze the regulation of HIF-1α following vascular and/or endovascular surgery in peripheral ...
Cihan Yücel, Mete Gürsoy, Serkan Ketenciler, Aslıhan Tenekeciğil, Feryaz Kızıltan, Nihan Kayalar   +5 more
doaj   +1 more source

Lipid Mediator Informatics and Proteomics in Inflammation-Resolution

The Scientific World Journal, 2006
Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu, Song Hong, Katherine Gotlinger, Charles Serhan   +3 more
doaj   +1 more source