Results 41 to 50 of about 432,839 (343)

Short-Vessel Occlusion Might Indicate Higher Possibility of Success in Reperfusion following Mechanical Thrombectomy in Acute Middle Cerebral Artery Occlusion

open access: yesCerebrovascular Diseases Extra, 2021
Background: The impact of the length of the occluded vessel in acute large-vessel occlusion on successful reperfusion by mechanical thrombectomy remains unclear.
Tomoyuki Yoshihara   +6 more
doaj   +1 more source

Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins

open access: yesThe Scientific World Journal, 2002
It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N. Serhan, Nan Chiang
doaj   +1 more source

Reperfusion injury

open access: yesClinical Cardiology, 1990
AbstractThis article reviews the early and late morphologic changes associated with reperfusion of ischemic myocardium. If instituted within minutes of coronary artery occlusion, all reversibly injured myocardium is salvaged. Once some irreversibly injured myocardium is present, the usually bland region of coagulation necrosis is transformed into an ...
openaire   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Heart defibrillation: relationship between pacing threshold and defibrillation probability

open access: yesBioMedical Engineering OnLine, 2019
Background Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation parameters to increase its efficiency.
Priscila C. Antoneli   +4 more
doaj   +1 more source

Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management

open access: yesFrontiers in Neurology, 2021
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed when certain areas of cerebral infarction appear as cerebral ...
Ji Man Hong   +3 more
doaj   +1 more source

Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological Strategies

open access: yesInternational Journal of Molecular Sciences, 2019
Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous concern in every transplantation proceeding, from whole organs to modest grafts.
Ricardo O S Soares   +4 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation

open access: yesMolecular Medicine
Background Specialized pro-resolving mediators (SPMs) promote resolution of inflammation, clear infections and stimulate tissue regeneration. These include resolvins, protectins, and maresins.
Charles N. Serhan   +2 more
doaj   +1 more source

Ischemia-Reperfusion Damage

open access: yesThe Eurasian Journal of Medicine, 2013
Ischemia-reperfusion damage is a complex pathological process that begins with tissue anoxia and continues with the production of free oxygen radicals, expanding with the inflammatory response. The literature suggests the importance of antioxidant and anti-inflammatory treatment to treat ischemia-reperfusion-related tissue damage.
Omer E, Yapca   +2 more
openaire   +2 more sources

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