Results 41 to 50 of about 382,913 (294)

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

Nature Communications, 2018
Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.
Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C. Norris, Nan Chiang, Charles N. Serhan   +7 more
doaj   +1 more source

Predictors of clinical outcomes after cardiac resynchronization therapy in patients ≥75 years of age: a retrospective cohort study

BMC Geriatrics, 2019
Background Cardiac resynchronization therapy has been shown to benefit selected patients with heart failure and reduced ejection fraction. Older patients have been underrepresented in randomized trials.
Laure Champ-Rigot, Anne-Laure Cornille, Pierre Ollitrault, Arnaud Pellissier, Mathieu Chequel, Damien Legallois, Paul Milliez   +6 more
doaj   +1 more source

Fortelyzin® in the treatment of ischemic stroke. Case report

Consilium Medicum, 2023
Given the current high incidence of cerebral circulatory disorders and the challenging treatment of such patients, developing therapies and medications for these conditions is urgent.
Sarbinaz T. Ubushieva, Dmitry N. Kazakov, Anastasiya Yu. Lebedeva   +2 more
doaj   +1 more source

Left ventricular function assessment using 123I/99mTc dual-isotope acquisition with two semi-conductor cadmium–zinc–telluride (CZT) cameras: a gated cardiac phantom study

EJNMMI Physics, 2016
Background The impact of increased energy resolution of cadmium–zinc–telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions (99mTc and 123I) remains unknown. The Amsterdam-gated dynamic cardiac phantom (AGATE,
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini, Alain Manrique   +5 more
doaj   +1 more source

Lipid Mediator Informatics and Proteomics in Inflammation-Resolution

The Scientific World Journal, 2006
Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu, Song Hong, Katherine Gotlinger, Charles Serhan   +3 more
doaj   +1 more source

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P, Headrick, John P., Neumann, David L., Peart, Jason N., Shum, David H K, Stapelberg, Nicolas J C   +5 more
core   +1 more source

Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins

The Scientific World Journal, 2002
It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N. Serhan, Nan Chiang
doaj   +1 more source

Reperfusion injury

Clinical Cardiology, 1990
AbstractThis article reviews the early and late morphologic changes associated with reperfusion of ischemic myocardium. If instituted within minutes of coronary artery occlusion, all reversibly injured myocardium is salvaged. Once some irreversibly injured myocardium is present, the usually bland region of coagulation necrosis is transformed into an ...
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Heart defibrillation: relationship between pacing threshold and defibrillation probability

BioMedical Engineering OnLine, 2019
Background Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation parameters to increase its efficiency.
Priscila C. Antoneli, Jair T. Goulart, Isabella Bonilha, Daniela D. de Carvalho, Pedro X. de Oliveira   +4 more
doaj   +1 more source