Results 141 to 150 of about 2,176,828 (392)

Mechanism of hepatic ischemia/reperfusion injury and protection against reperfusion injury

open access: yesTransplantation Proceedings, 2002
THE ISCHEMIA/REPERFUSION injury remains a problem after liver surgery or liver transplantation. Preservation injury is a major cause of primary nonfunction following liver transplantation. Sinusoidal endothelial cell (SEC) apoptosis is an outcome of cold ischemia/reperfusion injury.
openaire   +4 more sources

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

open access: yesAdvanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li   +9 more
wiley   +1 more source

Adenosine A1 receptor activation attenuates lung ischemia–reperfusion injury [PDF]

open access: yes, 2013
ObjectivesIschemia–reperfusion injury contributes significantly to morbidity and mortality in lung transplant patients. Currently, no therapeutic agents are clinically available to prevent ischemia–reperfusion injury, and treatment strategies are limited
Fernandez, Lucas G.   +4 more
core   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

open access: yesAdvanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang   +11 more
wiley   +1 more source

Inhibition of the cGAS–STING pathway: contributing to the treatment of cerebral ischemia-reperfusion injury

open access: yesNeural Regeneration Research
The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart, liver, brain, and kidney, but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically reviewed.
Hang Yang   +6 more
doaj   +1 more source

Uremic cardiomyopathy is characterised by loss of the cardioprotective effects of insulin [PDF]

open access: yes, 2012
Chronic kidney disease is associated with a unique cardiomyopathy, characterised by a combination of structural and cellular remodelling, and an enhanced susceptibility to ischaemia-reperfusion injury.
Anne-Marie L. Seymour   +7 more
core   +1 more source

Neuroprotective Mechanisms of Calycosin Against Focal Cerebral Ischemia and Reperfusion Injury in Rats

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Emerging evidence suggests that autophagy plays important roles in the pathophysiological processes of cerebral ischemia and reperfusion injury.
Yong Wang   +4 more
semanticscholar   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim   +12 more
wiley   +1 more source

Effect of hydroxyethyl starch on acute renal injury in a model of hepatic ischemia-reperfusion [PDF]

open access: yes, 2012
BACKGROUND: Hepatic vascular control techniques employed during liver surgery are usually associated with ischemia-reperfusion injury, which could cause acute renal dysfunction. The murine model has been used in the study of this injury.
Cabrita, A   +4 more
core  

Clinical manifestations and basic mechanisms of myocardial ischemia/reperfusion injury

open access: yesCi ji yi xue za zhi = Tzu-chi medical journal, 2018
Acute myocardial ischemia/reperfusion (I/R) injury is a significant, unsolved clinical puzzle. In the disease context of acute myocardial infarction, reperfusion remains the only effective strategy to salvage ischemic myocardium, but it also causes ...
Chiu-fen Yang
semanticscholar   +1 more source

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