Results 201 to 210 of about 2,074,884 (292)
Advanced Science, EarlyView.Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang +14 more
wiley +1 more source
Erratum to: Effect of Leptin and Apelin Preconditioning on Hepatic Ischemia Reperfusion Injury in Rats [PDF]
, 2012 Tamer Sağıroğlu +7 more
openalex +1 more source
Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase
Advanced Science, EarlyView.Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song +9 more
wiley +1 more source
“Time Is Brain” – for Cell Therapies
Advanced Science, EarlyView.The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin +4 more
wiley +1 more source
Research Progress on Idebenone in Neurodegenerative Diseases
AGING MEDICINE, EarlyView.The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang +10 more
wiley +1 more source
Correction to “PLK2 Inhibited Oxidative Stress and Ameliorated Hepatic Ischemia–Reperfusion Injury Through Phosphorylating GSK3β” [PDF]
openalex +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami +6 more
wiley +1 more source
Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs
Angewandte Chemie, EarlyView.A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee +4 more
wiley +2 more sources
Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]
, 2018 Bové +42 more
core +2 more sources