Results 211 to 220 of about 2,272,622 (291)

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang, Yan Teng, Fang‐Lan Yao, Shu‐Qi Wei, Yan Li   +4 more
wiley   +1 more source

Ferroptosis in ischemia-reperfusion injury: molecular mechanisms and therapeutic strategies. [PDF]

Am J Cardiovasc Dis
Wei YL, Cheng L, Chen XY, Qiao Q, Ye XR, Wang D, Zhang HL, Song ZJ, Wang W, Zhang JJ.   +9 more
europepmc   +1 more source

The Influence of Bromelain Administration on Pro-Inflammatory Cytokines and Lipid Peroxidation in a Rat Model of Intestinal Ischemia/Reperfusion Injury. [PDF]

Vet Med Sci
Gültekin Ç, Sayiner S, Çetinel Ş, Şehirli AÖ.   +3 more
europepmc   +1 more source

Eucalyptol attenuates testicular ischemia-reperfusion injury in rats. [PDF]

Vet Res Forum
Kirgiz O, Akcakavak FK, Akcakavak G, Alakus I, Alakus H, Yilmaz Deveci MZ, Karatas O, Coskun P.   +7 more
europepmc   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

HIF1A transcriptionally activates CDKN1A to drive ferroptosis in skeletal muscle ischaemia-reperfusion injury. [PDF]

J Orthop Translat
Zhou M, Wang K, Jin Y, Liu J, Xue Y, Wang Y, Jia X, Liu H, Wang P, Li Z, Pan X, Ma Y, Rui Y.   +12 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Naringenin improves testicular reproductive function in rats with testicular ischemia-reperfusion injury. [PDF]

Acta Cir Bras
Wei SM, Huang YM.
europepmc   +1 more source

The Drug Safety Framework of Avacopan: A Pharmacovigilance Study

Medicine Advances, EarlyView.
We identified 11 previously unreported potential adverse events associated with avacopan. No high‐priority clinical events were observed; however, special attention should be paid to the potential possibility of avacopan‐induced vanishing bile duct syndrome (Logos and icons displayed in the sections “Safety Framework” and “Data Sources and ...
Tianqi Chang, Xiaohong Xin, Xian Shao, Dikang Pan, Jingyu Wang   +4 more
wiley   +1 more source