Results 231 to 240 of about 199,564 (290)

Ethanol extracts from Portulaca oleracea L. attenuated ischemia/reperfusion induced rat neural injury through inhibition of HMGB1 induced inflammation.

, 2016
Chenggang Zheng, Chen Liu, Wanyin Wang, Gusheng Tang, Liwei Dong, Juan Zhou, Zhengrong Zhong   +6 more
openalex   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

iRhom2 regulates HMGB1 secretion to modulate inflammation and hepatocyte senescence in an in vitro model of ischemia-reperfusion injury. [PDF]

Cell Death Dis
Calligaris M, Perriera R, Carcione C, Miceli V, Pinto ML, Busà R, Amico G, Bulati M, Amato C, Pagano D, Conaldi PG, Scilabra SD, Pinzani M, Zito G.   +13 more
europepmc   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

STAT1 promotes ferroptosis and inflammation in mouse hepatic ischemia-reperfusion injury. [PDF]

Commun Biol
Wu K, Xu T, Jiang B, Yu X, Wang Y, Sun H, Zhao Z, Du M, Wang S, Ma L.   +9 more
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway. [PDF]

Eur J Med Res
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X.   +5 more
europepmc   +1 more source

Correction: Electroacupuncture Alleviates Cerebral Ischemia-Reperfusion Injury by Downregulating IL-17 A and Inhibiting Neurotoxic Astrocyte Activation. [PDF]

Neurochem Res
Zhao MM, Song Q, Xie QY, Sun WQ, Zhang Y, Tang W, Li MX.   +6 more
europepmc   +1 more source

Myocardial reperfusion injury.

Nihon Naika Gakkai Zasshi, 1992
openaire   +2 more sources

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source