Results 231 to 240 of about 2,074,884 (292)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

THE EFFECTS OF HYDROGEN GAS ON RENAL ISCHAEMIA REPERFUSION INJURY IN A PRE-CLINICAL MODEL

open access: green, 2018
Thomas Adams   +4 more
openalex   +1 more source

PEGylation of polymerized albumin retains colloid osmotic pressure: Towards an enhanced potential plasma substitute

open access: yesBiotechnology Progress, EarlyView.
Abstract Plasma expanders (PEs) are commonly used to replace lost blood volume for septic shock patients with increased vascular permeability. Human serum albumin (HSA) is the preferred PE, due to its innate ability to restore blood colloid osmotic pressure (COP).
Amna Abdalbaqi   +7 more
wiley   +1 more source

Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy

open access: yesJournal of Pineal Research, 2018
Hao Zhou   +5 more
semanticscholar   +1 more source

Scalable production and biophysical characterization of an enzyme cocktail derived from human red blood cells

open access: yesBiotechnology Progress, EarlyView.
Abstract Red blood cells (RBCs) play a critical role in oxygen and carbon dioxide transport, which is facilitated by RBC‐encapsulated hemoglobin (Hb) and carbonic anhydrase (CA). In addition, RBCs are constantly exposed to oxidative stress due to the intracellular reactive oxygen species (ROS) generated during Hb auto‐oxidation.
Mohd Asim Khan   +4 more
wiley   +1 more source

Effects of different ischemic preconditioning strategies on physiological and cellular mechanisms of intestinal ischemia/reperfusion injury: Implication from an isolated perfused rat small intestine model

open access: gold, 2021
Yuk Lung Wong   +11 more
openalex   +2 more sources

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller   +3 more
wiley   +1 more source

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