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Reperfusion Injury

Plastic and Reconstructive Surgery, 2006
The restoration of blood flow to ischemic tissues causes additional damage, which is termed reperfusion injury. All tissues are susceptible to reperfusion injury, but this susceptibility varies between tissues. Reperfusion has wide clinical relevance. It influences the outcome of patients after myocardial infarction, stroke, organ transplantation, and ...
Alizan A, Khalil   +2 more
openaire   +2 more sources

Reperfusion Injury

Critical Care Nursing Clinics of North America, 1991
The paradigm of reperfusion is one that will test the skills of the critical care practitioner. This syndrome has been implicated in many of the disorders commonly encountered in the intensive care unit. As research continues and more knowledge is gained into the evolution of this process, many of the complications caused by this affliction will be ...
W J, Quinones-Baldrich, D, Caswell
openaire   +2 more sources

Myocardial Reperfusion Injury

New England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
openaire   +5 more sources

Reperfusion Injury

Surgical Clinics of North America, 1992
In conclusion, a large body of evidence demonstrates that reperfusion of ischemic intestine results in significant microvascular and parenchymal cell injury. Reperfusion injury appears to be mediated by both reactive oxygen metabolites and activated polymorphonuclear leukocytes.
B J, Zimmerman, D N, Granger
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Mechanisms of Reperfusion Injury

The American Journal of the Medical Sciences, 1994
Reperfusion of ischemic organs can result in tissue injury that is manifested as microvascular and parenchymal cell dysfunction. Reactive oxygen metabolites and polymorphonuclear leukocytes (PMN) have been implicated in the pathobiology of reperfusion injury.
B J, Zimmerman, D N, Granger
openaire   +2 more sources

Pathophysiology of reperfusion injury

2011
INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellular dysfunction and death, following restoration of blood flow to previously ischaemic tissues. Reestablishment of blood flow is essential to salvage ischaemic tissues.
Cowled, P., Fitridge, R.
openaire   +2 more sources

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