Results 271 to 280 of about 340,285 (357)

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan   +3 more
wiley   +1 more source

From DNA Methylation Microarray to Digital PCR: A Stepwise Strategy for Tissue Specific cfDNA Biomarker Development

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Overview of a DNA methylation biomarker development pipeline, from discovery and assay design to screening, performance evaluation, and specificity testing in clinical sample matrices. ABSTRACT Background Tissue‐specific cell‐free DNA (cfDNA) offers promise as a minimally invasive biomarker of organ injury.
David H. Murray   +6 more
wiley   +1 more source

Trem1 regulates neutrophil metabolism and recruitment in lung ischemia-reperfusion injury. [PDF]

open access: yesRedox Biol
Yang F   +15 more
europepmc   +1 more source

Normothermic Machine Perfusion vs. Static Cold Storage for DBD Liver Transplantation in High‐MELD Recipients: A Single‐Center Retrospective Study

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Purpose While normothermic machine perfusion (NMP) has benefits over static cold storage (SCS), its efficacy in high‐acuity recipients with high Model for End‐Stage Liver Disease (MELD) scores, particularly using a back‐to‐base application model, is not well established.
Yuzuru Sambommatsu   +9 more
wiley   +1 more source

Periodontitis and high phosphate intake alone or in combination adversely affect the kidney

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis and high phosphate (HP) intake can negatively affect the kidney in the presence of renal disease. This study aimed to evaluate the effects of periodontitis or HP intake, either alone or concurrently, on the periodontal tissue and the kidney under normal renal conditions.
Ae Ri Kim   +4 more
wiley   +1 more source

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