Results 141 to 150 of about 4,697,552 (378)

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

Pretreatment Plasminogen Activator Inhibitor-1 (PAI-1) Level in the Failure of Streptokinase Therapy in Acute Myocardial Infaction

Journal of Research in Medical Sciences, 2004
Background: The risk for unsuccessful reperfusion after streptokinase therapy may be caused by the antifibrinolytic effect of platelet-derived type 1 plasminogen activator inhibitor (Pal-1) and antistreptokinase antibodies.
H Shemirani, M Tajmirriahi, A Rezaei, F Oreisi   +3 more
doaj  

Subclinical Hyperthyroidism Could Predict Poor Outcomes in Patients With Acute Ischemic Stroke Treated With Reperfusion Therapy

Frontiers in Neurology, 2019
Background: Evidence for the effect of subclinical thyroid dysfunction on the prognosis of patients suffering from acute ischemic stroke and receiving reperfusion therapy remains controversial.
Sang-Hwa Lee, Min Uk Jang, Yerim Kim, So Young Park, Chulho Kim, Yeo Jin Kim, Jong-Hee Sohn   +6 more
doaj   +1 more source

The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004 [PDF]

, 2006
Aims Our study aimed to examine the management of acute coronary syndromes (ACS) in Europe and the Mediterranean basin, and to compare adherence to guidelines with that reported in the first Euro Heart Survey on ACS (EHS-ACS-I), 4 years earlier ...
Battler, Alex, Behar, Shlomo, Bodonovits, István, Boyko, Valentina, Bueno, Hector, Csoti, Éva, Danchin, Nicolas, Filippatos, Gerasimos, Gitt, Anselm, Hasdai, David, Hasin, Yonathan, Kovács Szentes, Ferenc, Kovács, Aranka, Mandelzweig, Lori, Marrugat, Jaume, Préda, István, Takács, János, Wallentin, Lars, Werf, Frans, Van de   +18 more
core   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Acute stroke alert activation, emergency service use, and reperfusion therapy in Sweden

Brain and Behavior, 2017
Ambulance services and stroke alerts reduce the time from stroke onset to acute stroke diagnosis. We describe the use of stroke alerts and ambulance services in different hospitals and patient groups and their relationship with reperfusion therapy.
M. Eriksson, E. Glader, B. Norrving, B. Stegmayr, K. Asplund   +4 more
semanticscholar   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization

Advanced Science, EarlyView.
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim, Hyeok Kim, Dong‐Hyun Lee, Yeong Hwan Kim, Jae‐Hyun Park, Woo‐Sup Sim, Jin‐Ju Kim, Kiwon Ban, Soong Ho Um, Hyun Ji Park, Michael E. Davis, Hun‐Jun Park, Suk Ho Bhang   +12 more
wiley   +1 more source

The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]

, 2011
Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core