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Reperfusion therapies and poststroke seizures
Epilepsy & Behavior, 2020Seizures are not only a frequent complication of stroke but have been associated with an unfavorable functional and vital outcome of patients who have had stroke. Facing a new paradigm of acute standard stroke care, acute symptomatic seizures in this clinical setting deserve to be rethought.
Bentes, Carla +3 more
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Emergency Nurse, 2006
In this article Nick Castle explains that, with significant improvements being made to the emergency management of cardiac patients, emergency nurses should challenge and develop their clinical practice to ensure patients receive prompt and evidence based treatment.
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In this article Nick Castle explains that, with significant improvements being made to the emergency management of cardiac patients, emergency nurses should challenge and develop their clinical practice to ensure patients receive prompt and evidence based treatment.
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Reperfusion therapy for stroke
Australian and New Zealand Journal of Medicine, 1999AbstractStroke is a heterogenous disease, but about 85% of strokes are as a result of cerebral ischaemia due to arterial occlusion. It seems logical to assume that, as in myocardial infarction, treatment designed to dissolve clots should be helpful.We now have a substantial amount of data on the use of aspirin, heparin and thrombolytic drugs in the ...
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Reperfusion adjunctive therapy.
CHEST Journal, 1991The beneficial effects of coronary thrombolytic therapy may be enhanced by certain adjunctive therapies. Some of these are of proven value, some appear to offer no benefit in spite of theoretical advantages, and some remain to be evaluated in clinical trials.
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Microvascular integrity after reperfusion therapy
American Heart Journal, 1999Several perfusion techniques have definitively shown that microvascular dysfunction plays a crucial role in patients with acute myocardial infarction. In those patients, despite a rapid and sustained restoration of flow throughout a previously occluded epicardial coronary artery, microvascular damage still may be observed.
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Reperfusion Therapies for Acute Ischemic Stroke
Current Treatment Options in Neurology, 2010Ischemic stroke is most often caused by an acute extracranial or intracranial thromboembolic lesion obstructing an artery. It has been demonstrated that recanalization is the most important modifiable predictor of a good clinical outcome. Reperfusion strategies focus on early reopening of the vessel to reestablish antegrade flow within the penumbra ...
David, Goldemund, Robert, Mikulik
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Therapy Against Reperfusion-induced Microvascular Injury
Current Pharmaceutical Design, 2013No-reflow, i.e., the lack of distal myocardial perfusion to fully recover following recanalization of an acutely occluded coronary artery, is not only a mere consequence of ischemic injury, as substantial microvascular alterations may also develop subsequently, after initial restoration of perfusion.
TRITTO, Isabella +3 more
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Reperfusion therapy in acute cerebrovascular syndrome
Current Opinion in Neurology, 2011Modern reperfusion therapy in acute ischemic stroke therapy is based on an 'as fast as possible' recanalization approach to obtain favorable clinical outcomes. However, arterial recanalization may be achieved without favorable clinical outcome, raising the question of the target population to be treated.
Mikael, Mazighi, Pierre, Amarenco
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Pharmacological therapy for myocardial reperfusion injury
Current Opinion in Pharmacology, 2004In the ischemic myocardium, reperfusion is necessary for the salvage of cells and cardiac function. However, reperfusion itself causes 'reperfusion injury', leading to the damage of myocardial cells. This is reduced by several interventions, as measured by the limitation of infarct size or reduction of arrhythmias.
George V, Moukarbel +2 more
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Neurocytoprotection advances in reperfusion therapy
S.S. Korsakov Journal of Neurology and PsychiatryAcute stroke is the second leading cause of death and the third leading cause of disability in the world. Ischemic stroke (IS) the most common type of stroke. In acute cerebral ischemia, damage to the brain tissue is complex and includes blood-brain barrier (BBB) dysfunction, neuroinflammation, oxidative stress, activation of intracellular and ...
I.A. Shchukin +3 more
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