Results 111 to 120 of about 205,704 (259)

Plateforme Répertoire des écritures numériques

Nouveaux Cahiers de Marge
Plateforme Répertoire des écritures numériques
doaj   +1 more source

Emotion Regulation in Children and Adolescents with Social Anxiety Disorder: Differences in Strategy Use and Repertoire Compared to Specific Phobias and Healthy Controls. [PDF]

Res Child Adolesc Psychopathol
Ikas A, Rauschenbach AL, Hauffe V, Tuschen-Caffier B, Schmitz J.   +4 more
europepmc   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

Advanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang, Yixiang Deng, Nan Xia, Shuzo Sugita, Shangbang Gao   +4 more
wiley   +1 more source

The T-cell receptor repertoire of wild mice. [PDF]

Discov Immunol
Cohen JA, Hunter-Barnett S, Nageswaran G, Byrne S, Freeman G, Cowley MV, Chain B, Viney M.   +7 more
europepmc   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Quantitative evaluation of T-cell repertoire restoration following hematopoietic stem cell transplantation in patients with and without graft versus host disease. [PDF]

Front Immunol
Zhang X, Song P, Tang L, Ji X, Hu X, Ma X, Chen F, He X, Wang J, Li W, Qiu H, Xue S, Wang Y, Miao M, Chen S, Wu D, Tang X, Wang M, Wang W, Tian X.   +19 more
europepmc   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

Immunogenetic Architecture of Chronic Lymphocytic Leukemia at Early Stage: Insights from the O-CLL1 Cohort. [PDF]

Antibodies (Basel)
Bagnara D, Mazzarello AN, Colombo M, Nano E, Cardente N, Ferrero F, Bertola N, Cossu V, Ghiotto F, Ibatici A, Angelucci E, Neri A, Gentile M, Morabito F, Ferrarini M, Cutrona G, Fais F.   +16 more
europepmc   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

High throughput profiling of the B cell repertoire identifies systematic changes in the repertoire of individuals with Crohn's disease. [PDF]

Front Immunol
Mahdy AKH, Taheri Z, Høivik ML, Franke A, ElAbd H.   +4 more
europepmc   +1 more source