Results 121 to 130 of about 360,824 (309)

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Cooperative Cinema in Rural Distribution in Karelia in the 1920s

Финно-угорский мир
Introduction. The article examines films about cooperation that were part of the repertoire of cooperative film exhibitions for rural film distribution in Karelia. The relevance of the topic is determined by the visual turn in historical research and the
Elena V. Dianova
doaj   +1 more source

Repertoire Class: February 15, 1962 [PDF]

, 1962
This is the program for the Repertoire Class recital, February 15, 1962.
Division of Music, Repertoire Class
core  

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Repertoire Class: February 10, 1978 [PDF]

, 1978
This is the program for the Repertoire Class recital, held on February 10, 1978.
Division of Music, Repertoire Class
core  

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Identification of SARS-CoV-2-specific cytotoxic lymphocytes in cerebrospinal fluid of a patient with cerebral demyelination Post mRNA vaccination

Frontiers in Immunology
IntroductionSome cerebral demyelinating lesions occur after vaccination. We aimed to elucidate the precise roles of vaccine-activated immune cells and antigen-specific lymphocytes in the central nervous system of a patient who developed cerebral ...
Takaya Kitano, Takaya Kitano, Masakazu Ishikawa, Masakazu Ishikawa, Makoto Kinoshita, Keigo Kihara, Shuhei Sakakibara, Shuhei Sakakibara, Tomohiro Yata, Ryohei Yamamura, Hideki Mochizuki, Hideki Mochizuki, Masaru Yokoe, Tatsusada Okuno, Daisuke Okuzaki, Daisuke Okuzaki, Daisuke Okuzaki, Daisuke Okuzaki   +17 more
doaj   +1 more source

Repertoire Class: October 17, 1975 [PDF]

, 1975
This is the program for the Repertoire Class recital, held on October 17, 1975.
Division of Music, Repertoire Class
core  

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Multifactorial determinants of NK cell repertoire organization: insights into age, sex, KIR genotype, HLA typing, and CMV influence

Frontiers in Immunology
IntroductionPolymorphisms in the KIR and HLA genes contribute to the diversity of the NK cell repertoire. Extrinsic factors also play a role in modifying this repertoire. The best example is cytomegalovirus, which promotes the expansion of memory-like NK
Enora Ferron, Enora Ferron, Enora Ferron, Gaëlle David, Gaëlle David, Gaëlle David, Catherine Willem, Catherine Willem, Catherine Willem, Nolwenn Legrand, Nolwenn Legrand, Nolwenn Legrand, Perla Salameh, Perla Salameh, Perla Salameh, Laetitia Anquetil, Laetitia Anquetil, Alexandre Walencik, Alexandre Walencik, Ketevan Gendzekhadze, Katia Gagne, Katia Gagne, Katia Gagne, Katia Gagne, Christelle Retière, Christelle Retière, Christelle Retière   +26 more
doaj   +1 more source