Lymphocytes capable of making monoclonal autoantibodies that react with multiple organs are a common feature of the normal B cell repertoire. [PDF]
Bellur S. Prabhakar+3 more
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Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas+16 more
wiley +1 more source
Repertoire of antiviral antibodies expressed by somatic cell hybrids.
Walter Gerhard+3 more
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Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes. [PDF]
Linda A. Sherman
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This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen+11 more
wiley +1 more source
Trichomonas vaginalis NYH286 phenotypic variation may be coordinated for a repertoire of trichomonad surface immunogens [PDF]
J F Alderete
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Antibody repertoire and autoimmunity
Chrysanthi Skevaki, Duane R. Wesemann
openaire +2 more sources
Group 14 rhodamines are one of the most widely explored fluorogenic probes with high signal‐to‐noise ratio (SNR). We have boosted the SNR of group 14 rhodamines by nano‐aggregation via a novel strategy by manipulating their dynamic physical and chemical states for the first time. The ultrahigh SNR fluorescence imaging offers a fundamental understanding
Ning Wang+5 more
wiley +1 more source
Artificial Intelligences: A Bridge Toward Diverse Intelligence and Humanity's Future
Many discussions of artificial intelligence fail to address deeper questions being raised by advances in developmental biology, neuroscience, bioengineering, and philosophy of mind. Novel beings, including technologically and biologically augmented humans, engineered life forms, hybrots, and others, require tools of the emerging field of diverse ...
Michael Levin
wiley +1 more source
The B cell repertoire revealed by major histocompatibility complex-specific helper T cells. I. Frequencies of a genetically defined V region marker among mitogen- and T helper cell-reactive B lymphocytes in normal and immunized mice. [PDF]
Daniélé Primi+1 more
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