Results 151 to 160 of about 705,796 (337)

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

open access: yesAdvanced Science, EarlyView.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas   +16 more
wiley   +1 more source

Repertoire of antiviral antibodies expressed by somatic cell hybrids.

open access: green, 1978
Walter Gerhard   +3 more
openalex   +1 more source

Personalized Neoantigen Vaccine plus Regorafenib Increases Rgs2⁺CD8⁺ T Cells Infiltration and Reprograms the Tumor Microenvironment in Microsatellite Stable Colorectal Cancer Liver Metastases

open access: yesAdvanced Science, EarlyView.
This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen   +11 more
wiley   +1 more source

Antibody repertoire and autoimmunity

open access: yesJournal of Allergy and Clinical Immunology, 2023
Chrysanthi Skevaki, Duane R. Wesemann
openaire   +2 more sources

A General Strategy to Fine‐Tune Group 14 Rhodamines for Ultrahigh Signal‐to‐Noise Ratio Labeling In Vivo by Nano‐Aggregation

open access: yesAggregate, EarlyView.
Group 14 rhodamines are one of the most widely explored fluorogenic probes with high signal‐to‐noise ratio (SNR). We have boosted the SNR of group 14 rhodamines by nano‐aggregation via a novel strategy by manipulating their dynamic physical and chemical states for the first time. The ultrahigh SNR fluorescence imaging offers a fundamental understanding
Ning Wang   +5 more
wiley   +1 more source

Artificial Intelligences: A Bridge Toward Diverse Intelligence and Humanity's Future

open access: yesAdvanced Intelligent Systems, EarlyView.
Many discussions of artificial intelligence fail to address deeper questions being raised by advances in developmental biology, neuroscience, bioengineering, and philosophy of mind. Novel beings, including technologically and biologically augmented humans, engineered life forms, hybrots, and others, require tools of the emerging field of diverse ...
Michael Levin
wiley   +1 more source

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