Results 81 to 90 of about 819,894 (311)

Latent regulatory potential of human-specific repetitive elements [PDF]

, 2013
At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of
Barbosa-Morais, Nuno L., Blencowe, Benjamin J., Flicek, Paul, Kirschner, Kristina, Kutter, Claudia, Lukk, Margus, Menon, Suraj, Odom, Duncan T., Pan, Qun, Schmidt, Dominic, Schwalie, Petra C., Stark, Rory, Thybert, David, Ward, Michelle C., Watt, Stephen, Wilson, Michael D.   +15 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Repetitive Fractional-Order Active Disturbance Rejection Control for Permanent Magnet Synchronous Motor

Machines
In order to reduce the impact of various disturbances on the permanent magnet synchronous motor (PMSM) system especially during low-speed (0–300 rpm), this paper proposes a novel repetitive fractional-order active disturbance rejection control (RFO-ADRC)
Yi Zhao, Liang Guo, Jisong Zhang, Yu Zhou, Wenqi Lu   +4 more
doaj   +1 more source

Research of waveform control strategy for dual-stage power conversion system

Gong-kuang zidonghua, 2013
In view of problem of harmonic current existed in power conversion system with bi-directional energy control, an integrated current waveform control strategy based on dual-stage main circuit topology was proposed.
LU Sheng-li, JU Wen-yao, JIA Zhong-lu
doaj   +1 more source

On control laws for discrete linear repetitive processes with dynamic boundary conditions [PDF]

, 2008
Repetitive processes are characterized by a series of sweeps, termed passes, through a set of dynamics defined over a finite duration known as the pass length.
Galkowski, K, Hladowski, Lukasz, Rogers, E, Sule, V R   +3 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Research on compound current control strategy based on LCL type active power filter

Gong-kuang zidonghua, 2017
In view of contradiction between high steady state accuracy and fast dynamic response of traditional current control strategy, a novel compound current control strategy based on LCL type active power filter was proposed.
GAO Yunguang, SONG Jiancheng, ZHENG Lijun, JIANG Fayang, TIAN Feiyan   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

On controllability and control laws for discrete linear repetitive processes

, 2010
Repetitive processes are a distinct class of 2D systems (i.e. information propagation in two independent directions) of both systems theoretic and applications interest. They cannot be controlled by the direct extension of existing techniques from either
Galkowski, K, Hladowski, L, Owens, D H, Rogers, E   +3 more
core  

Iterative Nonlinear Control of a Semibatch Reactor. Stability Analysis [PDF]

, 2005
This paper presents the application of Iterative Nonlinear Model Predictive Control, INMPC, to a semibatch chemical reactor. The proposed control approach is derived from a model-based predictive control formulation which takes advantage of the ...
Bordons Alba, Carlos, Ramos Cueli, José
core