Results 41 to 50 of about 79,729 (116)

Global discovery and characterization of small non-coding RNAs in marine microalgae [PDF]

, 2014
Background Marine phytoplankton are responsible for 50% of the CO2 that is fixed annually worldwide and contribute massively to other biogeochemical cycles in the oceans. Diatoms and coccolithophores play a significant role as the base of the marine food
Beckers, Matthew, Dalmay, Tamas, Lopez-gomollon, Sara, Maumus, Florian, Mock, Thomas, Mohorianu, Irina, Moulton, Vincent, Moxon, Simon, Rathjen, Tina   +8 more
core   +4 more sources

Evolution of genes and repeats in the Nimrod superfamily [PDF]

, 2008
The recently identified Nimrod superfamily is characterized by the presence of a special type of EGF repeat, the NIM repeat, located right after a typical CCXGY/W amino acid motif.
Andrade, B. Sipos, Bork, Bork, Callebaut, Chen, D. Hultmark, Do, Doliana, E. Kurucz, Edgar, Evans, Finn, Guindon, Holt, Huelsenbeck, Hughes, I. Ando, J. Zsamboki, Ju, K. Somogyi, Kumar, Kumar, Kurucz, Liao, Mangahas, McAllister, Morgenstern, Nei, Nei, Nei, Nei, Nishikawa, Notredame, Ota, Parmley, Posada, Quesada, Redelings, Russo, Schuster-B  ckler, Simmons, Stajich, Strimmer, Swanson, Swidan, Thompson, Xia, Z. Penzes, Zdobnov, Zhang, Zou   +51 more
core   +1 more source

Clinical and genetic study of a juvenile⁃onset Huntington disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Background Huntington's disease (HD) is an autosomal dominant hereditary progressive neurodegenerative disorder with a distinct phenotype characterized by chorea, dementia, cognitive and affective impairment.
Ying HAO, Yuan⁃yuan CHEN, Wei⁃hong GU, Guo⁃xiang WANG, Hui⁃zi MA, Li⁃lin LI, Kang WANG, Miao JIN, Xiao⁃hui DUAN   +8 more
doaj  

Molecular biology techniques as a tool for detection and characterisation of Mycobacterium avium subsp. paratuberculosis [PDF]

, 2002
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) is the causative agent of paratuberculosis, also known as Johne’s disease, a chronic intestinal infection in cattle and other ruminants.
Englund, Stina
core  

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]

, 1986
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner, AHN Hopman, AL Jørgensen, AR Mitchell, B Trask, BU Zabel, CD Bloomfield, D Pinkel, GA Rappold, GA Rappold, H Hoehn, H. D. Hager, H. P. Scholl, HF Willard, J Wolfe, J. Landegent, JC Wu, JE Landegent, JE Landegent, L Manuelidis, LA Herzenberg, M Schardin, M Schmid, M Spaeter, M. Schardin, M. van der Ploeg, MM LeBeau, P Devilee, P Devilee, P. Devilee, P. Pearson, T Cremer, T. Cremer, W Schempp   +33 more
core   +1 more source

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization [PDF]

, 2013
The origin recognition complex (ORC) of Saccharomyces cerevisiae binds origin DNA and cooperates with Cdc6 and Cdt1 to load the replicative helicase MCM2–7 onto DNA. Helicase loading involves two MCM2–7 hexamers that assemble into a double hexamer around
A. Fernandez-Cid, A. Riera, Bell, Bowers, Bray, C. Evrin, C. Speck, Casas-Terradellas, Chen, Cocker, Coleman, Costa, Donovan, Dueber, Gillespie, Herbig, Holm, J. Zech, Klemm, Krupinski, Laemmli, Liang, Liang, Liu, M. C. Herrera, Mizushima, Neuwald, P. Clarke, Perkins, R. Lurz, Randell, Remus, Remus, Roy, S. Brill, Schepers, Seki, Singleton, Steven, Stoeber, Takara, Tanaka, Watanabe, Weinreich, Wendler, Williams, Ying, Zhang   +47 more
core   +1 more source

Protein Repeats from First Principles [PDF]

, 2016
Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence level. We use a mathematical definition
Becher, Veronica Andrea, Espada, Rocío, Ferreiro, Diego, Parra, Rodrigo Gonzalo, Turjanski, Pablo Guillermo   +4 more
core   +1 more source

Conserved noncoding sequences highlight shared components of regulatory networks in dicotyledonous plants [PDF]

, 2012
Conserved noncoding sequences (CNSs) in DNA are reliable pointers to regulatory elements controlling gene expression. Using a comparative genomics approach with four dicotyledonous plant species (Arabidopsis thaliana, papaya [Carica papaya], poplar ...
Barrington, Christopher, Baxter, Laura, Beynon, Jim, Buchanan-Wollaston, Vicky, Denby, Katherine J., Dyer, Nigel, Hickman, R. D. G., Jironkin, Aleksey, Krusche, Peter, Moore, Jonathan D., Ott, Sascha, Tiskin, Alexander   +11 more
core   +2 more sources

Capillary electrophoresis fragment analysis and clone sequencing in detection of dynamic mutations of spinocerebellar ataxia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To estimate the accuracy and stability of capillary electrophoresis fragment analysis and clone sequencing in detecting dynamic mutations of spinocerebellar ataxia (SCA). Methods Capillary electrophoresis fragment analysis and clone sequencing
Yuan-yuan CHEN, Ying HAO, Jin ZHANG, Xin ZHANG, Kun-ming XIE, Ming DING, Wei-hong GU   +6 more
doaj  

Detecting Repetitions and Periodicities in Proteins by Tiling the Structural Space [PDF]

, 2013
The notion of energy landscapes provides conceptual tools for understanding the complexities of protein folding and function. Energy Landscape Theory indicates that it is much easier to find sequences that satisfy the "Principle of Minimal Frustration ...
Espada, Rocío, Ferreiro, Diego U., Parra, R. Gonzalo, Sippl, Manfred J., Sánchez, Ignacio E.   +4 more
core   +2 more sources